Yes, in the sense that organic chemical reactions “create” new molecules. No, if it carries a creationist connotation and implies a creator. I think it is possible to use words like 'form', 'develop', 'polymerise', 'condense' etc. that imply only natural mechanisms.
You’ve asked how nucleotides might have arisen in the pre-biotic Earth. I don’t know the answer; it’s not my field.
But, from my point of view, there is nothing particularly unusual about a
nucleotide as an organic molecule. It is composed of phosphate, ribose and a purine or pyrimidine. Phosphate occurs naturally in the Earth’s crust. Purines and pyrimidines are merely cyclic or bicyclic nitrogen-containing compounds. I believe these sorts of cyclic organic molecules form naturally. Similarly, ribose is merely a simple carbohydrate.
..............................................................
Yes they are simple molecules ,but so far to make any of those simple molecules in controlled condition many steps are necessary. Some workers have claimed in succeeding in making them , were not able to repeat them .As you say " Purines and pyrimidines are merely cyclic or bicyclic nitrogen-containing compounds" but fine make an attempt to hook them up in a simple way with a ribose, or make an attempt to phosphorilate a ribose
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
I see no reason to believe that, given enough time, nucleotides could not have formed spontaneously via natural organic chemical reaction mechanisms.
..............
Sure , give me time . I prefer give me controlled conditions and in the lab we have controlled condition, but to make those molecules it takes many steps.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
Besides, there are hypotheses that state there were
self-replicating systems that pre-date nucleic acids and the “RNA world” and that drove the development of nucleic acids.
