Is it just that its more of a white genetic disorder? First black child with aging disease hopes for future The elfin child with the big personality and bright smile calls herself "the first lady" and dreams of the future. But doctors say 12-year-old Ontlametse Phalatse has only, perhaps, another couple of years to live. "I call myself a first lady because I'm the first black child with this disease ... Which other black child do you know with this disease?" she challenged. Ontlametse is the first black child diagnosed with progeria, a rare and fatal genetic condition that accelerates the aging process, the Progeria Research Foundation said.... Please Register or Log in to view the hidden image!
But isn't there a reason for sickle cell? People with sickle cell are more resistant to malaria. what would be the reason for the gene for progeria to develop?
That is an interesting question. Maybe it has something to do with preventing malignancies from developing. I've never heard of cancer or tumors in people with progeria.
or in people with Down Syndrome. But who cares if your not developing a tumor when you are dead by 13. Its not as if you are gonna have kids. Makes me wonder how that genetic disease developed at all.
umm suvival of the fittest? Thats how evolution works, its throws up "mestakes" and if the mestakes improve chance of suvival then it gets passed on, if it decreases your chances of suvival then you die without passing it on so its eliminated We can screw with that and alow mestakes to live longer and breed
While you are logically accurate in your statement above, in that our medical technology has enabled persons with abnormal genetics to potentially live longer and so possibly perpetuate those traits, by what scale of evaluation do we determine which genetic outcome is a 'mistake'? We tend to define 'normal' as a majority thing, yet is that really the direction that nature gives preference to? Depending on one's perspective, there are a lot of mistakes out there, and I am NOT referring to the differently abled. :bugeye:
These tragic rare cases probably have much to teach science about the mechanism of aging. I.e. it is more than just telomere shorting.
not getting into that, except to say there are some mestakes that should NEVER be alowed to be passed on (no matter what that means for the potentual parents). FFI and tay sachs for example should be wiped off the face of the plannet. That means that everyone from the family with FFI should be sterilised and everyone of jewish decent, cajun and french canadian tested for tay sachs and if they carry the gene also sterilised. Now minor mestakes on the other hand (such as myopia is oviously not a serious problem
Just wondering if your thoughts on that would be the same if you were in one of the genetic groups that you seem to think should be mandated sterilized? :bugeye:
Progeria has been associated with de novo mutations in the gene encoding a cytoskeletal protein called Lamin A. Cytoskeletal proteins are fundamental proteins in cellular biology and functioning and, thus, are conserved across all humans. Therefore I cannot see why Progeria would be more prevalent in one ethnicity over others. Given that it’s so rare, maybe random chance has skewed the small number of identified cases. :shrug:
YES!!!! Actually i would shoot myself in the head if i had FFI, if i carried the ressesive gene for tay sachs i would have MYSELF sterilised, if i had the disease itself it wouldnt matter because i wouldnt be alive past 2 years old. Those are links, read through what those diseases actually do
Aasguard, how do you interpret that I was speaking of your having the disease rather than just carrying the recessive from my reply above? I would suggest that you read and consider exactly the words that I have utilized in my reply. Words......my words......are quite precise. It is a slippery slope once you start down that path of determining whom should be sterilized and for what reasons. The selection bias could easily become convoluted. It could be suggested that obesity, bad spelling and bad manners are genetic disorders. Shouldn't be hard to fund a study to prove that point. Let's sterilize those groups also, it being so much more politically correct, as in gender and racial neutral...... Please Register or Log in to view the hidden image!
FFI is dominant, if you have it to pass on you have it to and god have mercy on you because its one of the worst diseases on earth. As i said if i found out i had the gene for that i would shoot myself. As for tay sachs Could i have been any clearer? There is no way i would want to father a child who by age 2 will be dead and will die in horrific amounts of pain. If i did have a child who had tay sachs i would kill them, no question asked even if it ment i went to jail for the rest of my life or even got the death pennelty. You cant even compare obsesity or "bad spelling" or myopia or red green colour blindness or any of a 100 other genetic conditions to those 2. Ebola might actually be kinder than those 2 diseases. BTW why did you quote those posts in the wrong order
The following words are credited to the child pictured in the O.P. Wise words from a child with a condition that likely condemns her to an early grave.
The chronology of the statements, in this case, is of less import than their content. They are arranged in the order which best conveys that message. You have made some very serious remarks in your recent post. I leave this conversation for a time......
