The Pharmacology Sticky

mikenostic said:
It is, but in different ways...


Yes, but while LSD might be more powerful than heroin per se, an overdose of LSD, while can make you go stark raving nuts, it usually won't kill you like an overdose of heroin, or crack can/will. Of all the celebrities who have died on a drug overdose, how many of them were from LSD, Read-only?
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An overdose isn't the point. You can die from drinking too much water (remember the woman in the drink - don't pee radio contest?).
 
Read-Only said:
An overdose isn't the point. You can die from drinking too much water (remember the woman in the drink - don't pee radio contest?).
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That's a bad analogy dude. You'd have to drink gallons and gallons of water for H2O poisoning. I'm well aware of it.
And yes, overdosing is the point because it has to do with the potentcy of a drug. Example, let's say there's a nasty little strain of heroin out there that if you took one dose of it at one time, it could kill you. IMO, that makes it more potent than a hit of acid (which would only make you trip for about 8 hours).

And I almost forgot about this one:
http://en.wikipedia.org/wiki/Atropine

Which has similar properties to this (which is classified as a chemical warfare hallucinogen):
http://www.thewednesdayreport.com/twr/bz.htm
 
The biggest danger with psychotropics is how seductive they are, from my reasearch I would put crack and crystal meth at the top of the list, perhaps followed by heroin. These 3 drugs are extremely seductive, powerful, short lasting and force the user to crave more and more hits. In the case of crack and meth they are so seductive that people can do them for days on end until they pass out from exhaustion, only to start all over again when they 'wake up' from their stupor, these drugs can kill within a few short years of chronic use completely consuming the subject by the time they die.
 
John J. Bannan said:
Is anyone seriously doing these drugs?
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Which ones?
I doubt anyone is doing atropine, as it's not a recreational drug. As for BZ, it's more of a chemical warfare agent, but does its job hallucinogenically. It's like LSD on steriods and crack (no pun intended). If it doesn't kill you, it can make you trip for months followed by some nasty psychosis.
I also doubt that anyone regularly doing crack, heroin, or meth would be a regular poster on here; they probably wouldn't have the coherency or the motivation.

these drugs can kill within a few short years of chronic use completely consuming the subject by the time they die.
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Heroin can kill you faster than in a few years.
 
spidergoat said:
LSD is most effective by weight, but I'm going to have to go with DMT, it is way more powerful. A possibile reason is that it is a native brain chemical.
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Agreed. In terms of potency by weight amount, LSD takes the cake. Only a few micrograms is enough to send someone into orbit.

Diphenhydramine I think messes people up the most because you hallucinate about 900 times more than LSD. And to a sober person you would seem way more out of it.
 
The most powerful is still legal. Salvinorin, derived from Salvia Divinorium. Makes DMT feel like milk and cookies.
 
The most powerful is still legal. Salvinorin, derived from Salvia Divinorium. Makes DMT feel like milk and cookies.
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"Pure" DMT shits all over Salvia, but they're also completely different. Preference, really.

- N
 
The report of Daniel Seibert first trying salvia is really funny. He thought it was intense but short acting until he realized that he was no longer in his lab, but his long dead grandmother's house, complete with her furniture!
 
well there are different levels of power. the power of addiction, the power of effect it has on the body, the power of effect it has on the mind. a combination of all of the above. and also you must always take into consideration that all drugs can effect different people in different ways. but a list of very potent and powerful drugs in my opinion are these.

LSD,
crack.
crystal meth.
herion.
MDMA.



peace.
 
John J. Bannan said:
What is the chemical properties of this drug that make it so powerful?
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Nobody knows. Most street drugs are mixed for the sake of our health. People react differently to different things. 100% pure cocaine is not the same as the coke you buy from "Jose". 100% pure coke will blow your heart and spew your eyes from their sockets. Chemical engineers can even make any drug more potent. By far the most dangerous are hallucigens, I don't know about most powerful.
 
Meth is the most powerful drug, I've seen what it does to people, its so powerful that it makes those who are addicted but without it a living hell, and life with it a blur of memories.

Yay, perhaps it is so powerful that slaves are being made left and right with this substance. Slaves that like to be slaves mind you... How fucked is that? Happiness in slavery?!?

I'd even go as far to say that meth presents the greatest human weakness of all: the want to be happy and feel good combined with the other extreme want to not feel a groggy hell
 
The most powerful drug would probably be the one with the lowest LD50 toxicity. It seems that LSD is in the lead here. I've heard that meth is also one of the most dangerous.
 
I'll agree with sci, and say meth. That shit will age you 20 years in a few months...if "powerful" means screwing your life up the quickest.

faces-of-meth.jpg
 
According to the bible of drug using comedies " Fear and loathing in Las Vegas", Ether is the most powerful and depraving drug-a real low life commodity. Adrenoquine is also up there. But like I said, many drugs are not 100%. We don't even have 100%alchohol. Abusing 100% alchohol will make you pass out into a coma for 40 days, and you will wake up with temporary amnesia.
 
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