"My opinion of the creature is that it is a hybrid of a human mother and an unknown hominid male, Just as reported. For all practical purposes, it should be treated as human and protected under law.
Brien, selection of Melba's lab for your studies is a very good call.
Sasquatch is real, as proven by genetic analysis."
Sounds like confirmation to me. Thanks for posting that.
Here's a number of independent confirmations of the Ketchum's DNA studies:
]http://www.sasquatchgenomeproject.org/sasquatch_genome_project_004.htm
As for your critique of the study by some anonymous scientist? Here's the response:
1. Please name this friend so we may examine his/her credentials.
2. These comments obvious originated from the first peer review done by the Journal Nature that were unethical leaked by one of the reviews.
3. The Novel North American Hominins, Next Generation Sequencing of Three Whole Genomes and Associated Studies was revised twice since this review.
4. All of his concerns were addressed ad nauseum in both the DNA Study and the peer reviews responses yet your "expert" predictably ignores them and the documentation.
Below is a paragraph from Dr. Ketchum's cover letter to the Journal Nature dated December 19th, 2012. It addresses most of the concerns of your unknown friend with a "Ph.D. from Harvard"
Reviewers accused our genomes of having contamination even though we went to great lengths to explain how the samples were extracted and screened to rule out contamination. To tell us, as scientists, especially those of us that are forensic scientists, that our samples are contaminated can be likened to accusing us of hoaxing a scientific study or perjuring ourselves in court. As forensic scientists that testify in court, this can be highly damaging and has caused all of the authors tremendous worry and concern. Since we were not given a chance to defend ourselves on the second peer review and our manuscript refused because of these
accusations (since all other revisions were verbiage and extremely minor), we contacted Illumina (manufacturers of the HiSeq 2000 next generation sequencing platform that we used to sequence the genomes) in an effort to prove, once and for all, that the three genomes were single source and not contaminated. We spoke with two supervisors specializing in technical support for next generation
DNA Diagnostics
P.O. Box 805
Garrison, Texas 75946
1-936-554-2116
http:
www.dnadiagnostics.com
sequencing. We asked them if it was possible to prove if there was contamination in a genome or not. They immediately answered “yes”! They told us that the average Q30 score for a genome was 85, but if there was contamination, which would cause the divergent sequences to compete against one another, that a contaminated sample would have a Q30 score of only 40 to 50. A pure, single source sample would have a Q30 score of about 85. When we checked our Q30 scores for the first read, our three genomes had Q30 scores of 92, 88 and 89 respectively. The second read was a little lower 88, 84.25 and 83.66 but still very close to the average of 85. The Q30 is the percent of the reads that have the statistical probability greater than 1:1000 of being correctly sequenced.
Therefore, with the help of the scientists at Illumina, it was determined that not only were the sequences from a single source, but the quality of the sequences were far above the average genome sequenced using their platform. I can furnish contact information if you desire it. We attribute the high quality of the genomes to the stringent extraction procedures utilized whereby the DNA was repeatedly purified. This gave us greater than 30X coverage of the three genomes.
Furthermore, it supported our original findings of human mitochondrial DNA since the whole genomes yielded human mitochondrial DNA consistent with the original individual mtDNA genome sequencing. The nuDNA findings were also supported in that there was novel primate sequence in the nuDNA. So, the original submission was indeed supported by the next generation sequencing that we included in the revised submission. The three genomes aligned with one another also supporting that all three genomes came from the same species and they were NOT contaminated. Most importantly, the Q30 scores absolutely disproved the reviewers’ assumption that the whole genomes were a mixture of
human with animal DNA contaminants. The summary of the next generation
sequencing generated by the Illumina HiSeq 2000 sequencer is now furnished as Supplementary Data 7 to support this discussion that is now included in our manuscript, Lines 544-558.=====
http://bigfootbooksblog.blogspot.com.au/2013/09/melba-is-toast-biochemist-with-phd-from.html