So how did the trans fat debacle happen? It's completely normal and routine, now and throughout human history, for the long view to be excluded from high pressure short term decision making. It takes special procedures, usually deliberate effort and designed interference from an outside agency with sufficient power, to prevent that. One central problem is that genetics reproduce themselves, spread themselves, escape and expand and invade on their own. The analogy with economic innovation informs, but underestimates the potential. The analogy of using fission bombs to blow subway tunnels downplays and underplays the kind of trouble possible, in at least two ways: tunnels so blown will come to an end and stop, they cannot recreate the bomb at the far end and blow themselves extensions. such tunnel blowing is publicly controlled, large scale and simple and overt, requires local political permission and the knowledge or input of many scattered, unrelated people. No self replicating tunnel-blowing agency can get started from somebody's back forty without even the neighbors knowing about it.