Nice to know, PHP. I'm disabled for depression, and none of the med's I've ever taken for depression worked (about 20 of them). Maybe that was because the serotonin-increasing drugs I was given weren't treating the problem, the problem being that the serotonin receptors (like the 1B receptor referenced in your article) weren't able to recieve the extra serotonin. This p11 protein will hopefully be the answer some day, if not for me, for future generations like me. Please, I volunteer for your research, if you are reading this. Please Register or Log in to view the hidden image! Seriously.