Why we shiver in the cold

S.A.M.

S.A.M.

uniquely dreadful
Valued Senior Member
We have specialised cold-sensing neurons with a single protein called TRPM8.

These cold sensing neurons are hypothesised to be of two types: (i) those sensing the cool sensation and (ii) those sensing pain related to cold (e.g. frostbite)

Scientists at the University of Southern California engineered mice so that neuron fibres that expressed this protein (TRPM8) would be fluorescent green.

They found that both types of cold sensing neurons (i and ii) expressed the same protein. So apparently both types of neurons express the same protein but have different functions.

http://timesofindia.indiatimes.com/Why_we_shiver_when_its_cold/articleshow/2635721.cms
 
So when someone has hypothermia is there a reduction or cessation in the function of these neurons? Are these neurons similar or the same as those that detect heat? That is, does TRPM8 react to all temperatures or just "cold" temperatures?
 
I think cold-sensing neurons sort of covers that :)

Hmm dunno about heat sensing neurons.
 
Hah. Got it. I'll admit that I have a limited knowledge of biology. Well, everything really, but I'm working on that! Interesting article though.
 
S.A.M. said:
These cold sensing neurons are hypothesised to be of two types: (i) those sensing the cool sensation and (ii) those sensing pain related to cold (e.g. frostbite)
Click to expand...

How come people came up with the idea that sensing cold and sensing pain are two different things in the first place?
 
I recently saw a TV documentary about Tibeten monks that were able to be

in a very cold room and had very cold towels put on them but after awhile

they all had those towels steaming somehow from a deep meditation they

were taught. The mind is a very powerful thing and this was something that

shows just how powerful it is. I'm sorry I can't find any links about this but

perhaps one of you that read this could, thanks. BTW the monks were

naked except for the towels and there wasn't any visible form of fire or heat

anywhere inside the primitive hut they were gathered in.
 
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