Where does the embryo store the memory of the development of the whole organism into a single system?

Yes. That is all encoded in the DNA.

The question you have asked is basically an entire field called embryonic development. It is very complex, and not easily encapsulated in a few paragraphs. It would take many books to cover it.

It is not as simple as "Here is the gene that will make you 5'11". It is more like:
- these 5,000 genes - that you got from your parents - and that are in every single cell in your body - all work together to produce growth, among many other things.
- the cells in your bones get signals from some of the genes to divide and grow. Other cells, in your muscles, get signals from other genes to divide and grow.
- some of these genes remain dormant for a time, and are then activated by hormones from the pituitary gland at the onset of puberty, causing tissue/bone growth for a time.
- when the pituitary gland stops putting out growth hormones in your late teens, some of these other genes are activated, switching off the growth (cell division) phase, causing your height to plateau.

It is way, way more complicated than that but the key takeaway is that this is ongoing all the time by genes switching other genes on and off as you grow.

Your height, as just one example, is not fixed in your genes. It is a process, occurring over time, that is set in motion by - and mediated by - your genes, influenced by your life, through such things as nutrition.


How much research have you done? Do you have any specific questions that have come out of your reading on the subject?
Ага, мне интересно, когда человек получает от родителей разные гены, например, от одного ген доброты, а от другого ген агрессивности - как они проявляются в одном человеке? Что влияет на то, что одни гены выключат другие? Т.е., человек будет либо добрым, либо злым?
 
Yeah, I wonder, when a person gets different genes from their parents, for example, from one the gene of kindness, and from another the gene of aggression - how do they manifest themselves in one person? What influences the fact that some genes will turn off others? That is, a person will be either kind or evil?
There aren't genes for kindness, though there are genes for sociability, which nurtures kindness.

This has a lot more to do with nurture than nature. Everybody has empathy and jealousy in them; nurture is what influences which they choose to manifest.
 
There aren't genes for kindness, though there are genes for sociability, which nurtures kindness.

This has a lot more to do with nurture than nature. Everybody has empathy and jealousy in them; nurture is what influences which they choose to manifest.
Ничего подобного, полно случаев, когда близнецы, выросшие вместе и получившие одинаковое воспитание, имели абсолютно разный характер.
 
I think of it as a biochemical cascade starting a multitude of processes, with triggering conditions for starts and feedbacks for stops to particular growth sequences - eg threshold tensions on micro-tubules triggering chromosomes to separate and produce messenger molecules that make their way along them to the other end with a 'stop' signal. The microtubule tension pulls them apart during cell division -


(Drew Barry's animations of biochemical processes are awesome - what is being represented is amazing but not something I think any intelligence could design).

There is no 'blueprint' or any 'memory' as such, yet key sequences of DNA hold the key triggers and other sequences of DNA are triggered in turn; no outside (God) agency involved or required. Very complex, yes, yet each reaction (molecules binding to other molecules in specific ways, which may result in a new one - or in several - making the necessary components and triggers for other combinations. Not random combinings and breaking apart but very specific sequences of reactions.
 
I think of it as a biochemical cascade starting a multitude of processes, with triggering conditions for starts and feedbacks for stops to particular growth sequences - eg threshold tensions on micro-tubules triggering chromosomes to separate and produce messenger molecules that make their way along them to the other end with a 'stop' signal. The microtubule tension pulls them apart during cell division -


(Drew Barry's animations of biochemical processes are awesome - what is being represented is amazing but not something I think any intelligence could design).

There is no 'blueprint' or any 'memory' as such, yet key sequences of DNA hold the key triggers and other sequences of DNA are triggered in turn; no outside (God) agency involved or required. Very complex, yes, yet each reaction (molecules binding to other molecules in specific ways, which may result in a new one - or in several - making the necessary components and triggers for other combinations. Not random combinings and breaking apart but very specific sequences of reactions.
Oh God, I now await the arrival of Write4U to administer the coup de grace to this thread:eek:.
 
You're wandering. I came here to discuss the thread topic.

So are you satisfied you have an answer to the question in the thread title?
Я не увидела полноценного ответа. Мне непонятно, по какому принципу активируются, или выключаются те, или иные гены.
 
I didn't see a full answer. I don't understand by what principle certain genes are activated or switched off.
The short answer is: by the action of other genes.

1. Imagine getting a box under the Christmas tree that has one instruction on it: 'Open this on box Christmas Day'.
2. On Christmas Day you open the box, and inside is some treats and gizmos and some mysterious coloured boxes with no labels on them.
3. One of the boxes, a Green one has a note attached that says 'Open this box on Boxing Day'.
4. On Boxing Day, you open the Green box, and inside is a note in it that says "Open the Red Box and the Blue Box."
5. Inside the Red Box is more trinkets that attach to the first gizmos. There are instructions to throw away the wrappers that the gizmos came in.
6. Inside the Blue Box is more treats.
7. It also has a note that says "On the 27th, take the wrappers from the treats you ate on Christmas Day and put them in the Yellow Box. Close the yellow box and set it aside and await further instructions."
8. etc. etc.


Again, that is the subject of whole books.
 
The short answer is: by the action of other genes.

1. Imagine getting a box under the Christmas tree that has one instruction on it: 'Open this on box Christmas Day'.
2. On Christmas Day you open the box, and inside is some treats and gizmos and some mysterious coloured boxes with no labels on them.
3. One of the boxes, a Green one has a note attached that says 'Open this box on Boxing Day'.
4. On Boxing Day, you open the Green box, and inside is a note in it that says "Open the Red Box and the Blue Box."
5. Inside the Red Box is more trinkets that attach to the first gizmos. There are instructions to throw away the wrappers that the gizmos came in.
6. Inside the Blue Box is more treats.
7. It also has a note that says "On the 27th, take the wrappers from the treats you ate on Christmas Day and put them in the Yellow Box. Close the yellow box and set it aside and await further instructions."
8. etc. etc.


Again, that is the subject of whole books.
Нам от предков достаются определённые гены. Например, способности к математике, или музыке. И склонность к определённым болезням тоже. Например, к алкоголизму. Как родитель алкоголик передаёт свои пороки детям?
 
We inherit certain genes from our ancestors. For example, abilities in mathematics or music. And a tendency to certain diseases, too. For example, to alcoholism. How does an alcoholic parent pass on their vices to their children?
There are genes related to alcoholic metabolism, yes.

Aptitudes like math and artistic talent are more subtle. My family has a predisposition for artistry. We probably inherited our large, well-connected, visual cortexes and hand-eye coordination from our father , but that's no guarantee we will all be painters. Some of us are musically- inclined.

Are ou satisfied that growing cells don't need to have "memory storage"?
 
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There are genes related to alcoholic metabolism, yes.

Aptitudes like math and artistic talent are more subtle. My family has a predisposition for artistry. We probably inherited our large, well-connected, visual cortexes and hand-eye coordination from our father , but that's no guarantee we will all be painters. Some of us are musically- inclined.

Are ou satisfied that growing cells don't need to have "memory storage"?
А кому нужно "хранилище памяти"? Что это вообще такое - "хранилище памяти"? Как оно выглядит?
 
Who needs a "memory storage"? What is a "memory storage" anyway? What does it look like?
Exactly.

So, yes, you have an answer to the question you asked in the opening post. You have realized the errors in the assertions you made there. Just wanted to ensure we had closure on that issue.
 
Exactly.

So, yes, you have an answer to the question you asked in the opening post. You have realized the errors in the assertions you made there. Just wanted to ensure we had closure on that issue.
Я не закрыла. Вы не ответили на вопрос: что такое память в вашем понимании?
 
I didn't close it. You didn't answer the question.
The question asked was Where does the embryo store the memory of the development of the whole organism into a single system?

That's been answered. You're welcome to continue to discuss the broader issue of memory if you wish, it just doesn't really interest me.
 
I am talking about the sequence of stages of embryonic development. It exactly repeats the evolution of human development. I read somewhere that at some stage the embryo even has a tail, which then disappears.

This is called "recapitulation theory" and is something currently discredited.

(the embryos of humans and those of other tail-less apes do have tails, though)

There is some superficial similarity between ontogenic stages and evolutionary/phylogenetic history, but it's not like the embryonic stages are functional mini-adults of ancestors, but rather a coincidence from some later evolutionary stages being largely additions to more basic, simpler homologue forms.

The evolution of the phenotype occurs through changes in embryonic development, and it's pretty much untenable that it would somehow manage to re-shape itself to the point of creating early embryos that look like perfect miniature adults of the current species rather than inheriting large chunks of early embryonic development and changing things more gradually, often near the final stages of development.

It's not really about "memory" of the lineage's evolution beyond the degree we can say that a species genome itself is a "memory" that retains a majority of ancestral genes dictating development, evolutionary divergence being determined only by a small fraction of genes and frequently affecting in the short evolutionary term mostly the later stages of embryonic development.

It's almost like fossils are "memories" of the Earth, only a metaphor.
 
I didn't see a full answer. I don't understand by what principle certain genes are activated or switched off.
The process here is:

- DNA is the pattern.
- An RNA polymerase molecule comes along and "unzips" the DNA strand at a specific spot.
- The polymerase creates mRNA (the antisense of the DNA) from the unzipped DNA.
- The mRNA moves away from the nucleus.
- A ribosome finds the mRNA and transcribes a protein.
- The protein folds itself and becomes functional.
- Proteins then determine what the next polymerase targets.

That's all VERY simplified of course. But as cells develop they specialize, and that specialization is caused by different proteins being expressed. Those proteins both determine the function of the cell and the next proteins that are transcribed.
 
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