I think you need to watch a plumber work, and then decide. How is a plumber going to custom bend titanium pipes to fit curvatures exactly?
I've seen plumbers with pipe benders match up radiators nice and easily. You would have to have pre-bent standard radii joints if you used titanium, and that would be incredibly restrictive, and reduce the options for placing things.
I would at least think the titanium could be placed for the long underground water-ways.
Also, copper being soft, it seals at joints nicely, and solders really easily too.. Titanium being hard, would require 'o' rings, and they perish and fail eventually, so you've traded a maintenance problem there.
This could be solved with having a steel end and outter wall, but a titanium inner coated shaft. (for the pipes that go from main supply to house) This would majorly reduce the intake of corroded metals into drinking water. I live in a house that was built in 1967 and already the water tastes of metal. Once we went on vacation and returned after about 2 weeks of no use and the water was rust colored until after a good rushing out period.