exchemist
Valued Senior Member
OK, yes.I think it rather indicates that the risk of severe symptoms from a COVID infection are higher for diabetics.
OK, yes.I think it rather indicates that the risk of severe symptoms from a COVID infection are higher for diabetics.
What can make Omicron not reach to Lungs or other tissues where ACE 2 receptors are there throug which its origibal counterparts take entry? Is it intrinsically different to COVID 19 in this characteristic?It seems to be not entirely clear yet whether the apparent decreased severity of the Omicron variant is due to intrinsically milder effects, or that its incidence to date may be mainly among younger people and those who already have some immunity (from vaccination or previous infection with other variants). There have been some studies that seem to show it does not go for the lungs in the same way as previous variants. (It is the lung damage that causes most of the severe disease.) And the symptoms of Omicron are apparently much closer to what one gets with a "normal" cold or 'flu' - runny nose, sore throat etc., which would fit with those findings.
One thing is clear: even though it is not very good at preventing infection with this variant, vaccination does give good protection against severe disease. So vaccination remains a high priority.
Good question. I don't know. I'll try to find out.What can make Omicron not reach to Lungs or other tissues where ACE 2 receptors are there throug which its origibal counterparts take entry? Is it intrinsically different to COVID 19 in this characteristic?
It does reach the lungs. But compared to Delta, it grows much faster in the bronchi and much slower in the lungs (alveoli.)What can make Omicron not reach to Lungs or other tissues
Sort of. It evolves to be more contagious. That can be via changes to the structure of the virus, or it could be due to worsening symptoms (which spread the disease) or it could be due to letting that sick guy walk around for years spreading it.However since Omicron show a trend toward decreased severity and fatality in proportion as compared to Covid 19 or Delta [ though increase in spread] we can have some hope that it may ne naturally slecting itself as Mr. Darwin has called 'natural selection', or the preservation of favoured races in the struggle for life. This goal can not be achieved unless both host ( humans and virus ) survive.
OK from an expert elsewhere I gather all variants use ACE2 to dock with the cell. What happens next is there has to be a way to gain entry. Here it seems there is evidence that Omicron may use a different method of entry from previous variants and this method does not favour lung cells. But it seems to be work still in progress, i.e. we don't know for sure yet.What can make Omicron not reach to Lungs or other tissues where ACE 2 receptors are there throug which its origibal counterparts take entry? Is it intrinsically different to COVID 19 in this characteristic?
Don't harmful virus evolve to become harmless virus to us...healthy human virome? It is also in their survival interest.Sort of. It evolves to be more contagious. That can be via changes to the structure of the virus, or it could be due to worsening symptoms (which spread the disease) or it could be due to letting that sick guy walk around for years spreading it.
So about all you can say is that it will evolve to kill people less quickly. Which is better than more quickly. But keep in mind that almost everyone survives HIV infection now. Is that something we want COVID to evolve towards? I mean, imagine HIV but spread through the air.
Thanks. However it is very important point, need full attention. I think in many cases of Covid, it also happen that their lungs are not infected. But yhere, it is due to some interference of immune response. But in Omicron it appear to be a different reason because every patient infected with it experisnce this type of outcome. Either omicron is wéaker variant than Delta so unable to reach in lungs or use some different route for entry.OK from an expert elsewhere I gather all variants use ACE2 to dock with the cell. What happens next is there has to be a way to gain entry. Here it seems there is evidence that Omicron may use a different method of entry from previous variants and this method does not favour lung cells. But it seems to be work still in progress, i.e. we don't know for sure yet.
We need to know it if it us due to difference in nature of Omicron variant or of our tissues or our immune response at these two sites.It does reach the lungs. But compared to Delta, it grows much faster in the bronchi and much slower in the lungs (alveoli.)
We will know soon enough. But give it a few months.We need to know it if it us due to difference in nature of Omicron variant or of our tissues or our immune response at these two sites.
Not really. A virus that cannot spread is a failure. Thus it is to its advantage to make us sick enough to spread, but not sick enough to kill us quickly.Don't harmful virus evolve to become harmless virus to us...healthy human virome? It is also in their survival interest.
?? It is, of course, due to both. Almost every virus in the world will kill someone with no immune system.We need to know it if it us due to difference in nature of Omicron variant or of our tissues or our immune response at these two sites.
However since Omicron show a trend toward decreased severity and fatality in proportion as compared to Covid 19 or Delta [ though increase in spread] we can have some hope that it may ne naturally slecting itself as Mr. Darwin has called 'natural selection', or the preservation of favoured races in the struggle for life.
I feel I am able tohttps://www.nature.com/articles/d41586-022-00039-0 find some here:.We will know soon enough. But give it a few months.
We will know soon enough. But give it a few months.
I can not say, whether demostration of Omricron variant suggest if Covid virus is gaining power or losing oower if gaining then it us foe if losing them friend or at least not foe. Not so?Not really. A virus that cannot spread is a failure. Thus it is to its advantage to make us sick enough to spread, but not sick enough to kill us quickly.
?? It is, of course, due to both. Almost every virus in the world will kill someone with no immune system.
Again, I disagree there. It's an improvement. It does not make omicron "a friend."I can not say, whether demostration of Omricron variant suggest if Covid virus is gaining power or losing oower if gaining then it us foe if losing them friend or at least not foe. Not so?
Is it not true that by bringing Omicron, Covid Virus has increased its presence(spread) but at the cost of reducing its vitality? It it not in our favor?Again, I disagree there. It's an improvement. It does not make omicron "a friend."
If a serial killer who was killing 10 women a year cut back to 5 a year, would you call him a friend? Because fewer are dying?
We need to be clear, that isn't friendly. Moreover, it's complete balderdash. Covid 19 is a virus; it isn't alive and cannot select itself as such.
The virus does not necessarily favor humans. Like I said, coronavirus has a wicked history:
There is no manner of calling Covid 19 Omicron a friend that does not require an extraordinary definition of friendship. The idea that the question would even be structured as such very nearly seems to be its own question.
The link between these pathogens remained hidden until the 1960s, when researchers in the United Kingdom and the United States isolated two viruses with crown-like structures causing common colds in humans. Scientists soon noticed
Yes I know but this is all preliminary. Need to wait for more studies.I feel I am able tohttps://www.nature.com/articles/d41586-022-00039-0 find some here:.
Probably it is due to variatiion in exoression of TMPRSS2 expression. Somewhat indicated here;
https://www.nature.com/articles/d41586-022-00039-0
It changes due to age,gender, diseases, smóking, lifestyke etc.
Like friendly bacteria are there few virus which can also be friendly to us?
However I am just comparing Omicron with Covid 19 or with Delta. If it is less harmful to us than its previous variants and is setting a trend toward making Covid less or non harmful by decreasing severity to us and reducing its own vitality then we can consider it is favouring us...so a friend. Not so?
Yes I know but this is all preliminary. Need to wait for more studies.