There is a tipping point in the human body such that if reached the immune system in the body cannot recover and eventually heal the body.
I suspect that the human species tipping point might have been the Industrial Revolution.
I think the tipping point is a long way off. Humans are fairly resourceful and can survive in a degraded environment. Even nuclear war might not wipe humans out.
For me the question is are we making life happier or more miserable for the future generations. Science is still advancing and this advancement is a gift to future generations but we are using up natural resources like soil and we are overpopulating and we are leaving pollution and leaving nuclear power plants that will need to be babysitted for thousands of years.