Films and movies, but people forget they were a script or a book to start with.
For instance George Orwell's "1984", that changed the perception of the world or some people. It's constantly bantered about with "Big Brother" being the keyword of phrase constantly bomabarding the press releases from one psychological experiment to the next.
Another, What of Isaac Asimov's Rules of Robotics (Was it "Metropolis"?), which is now apart of conversation when people discuss cyybernetics or artificial intelligence design.
How about Mary Shelly's "Frankenstein", the subject of cloning now might not have been such an abomination if it wasn't for the understanding that such a creation might be percieved a "monster" and scorned by the world.
There have been countless apocolyptic films ("Like Mad Max") perhaps this has allowed man to realise that blowing himself to oblivion isn't the best idea to make, so we've manage to keep most of the world in one piece, even ended a Cold war.
Science fiction can be based on science fact, and some authors (notibly P. K. Dick) mentioned that it's all very well to build a utopian world like Gene Roddenbery did, but they found the worlds to be made more interesting when that Utopia starts to fall to bits.
People have always seen what horrific events could befoul them from decay and chaos, and it has taught them caution in what they do.
So in short, Fiction does help mold fact, Either as inspiration to help pioneer or just to make sure we don't make so many mistakes.