Francine, No. Please explain. What controls? People have idiosyncracies. If they are screened beforehand for any symptoms like that. If they identify them beforehand, making them valid to use if they appear during the proving. Or, people with idiosyncracies excluded. I see the need for pilot runs anyway, just by the Homeopaths to test the quality of their procedures and medicines. They would also identify the provers most useful to the "Real" run. Once all that sorted out, modify expt for DBPC. Returning to Aph 117, there is likely to be a problem trying to exclude people with idiosyncracies, as these may be the symptoms most important (peculiar) to the medicine.