Tell me, It is wrong on Infection?

Discussion in 'Biology & Genetics' started by KUMAR5, Apr 28, 2020.

  1. Jeeves Valued Senior Member

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    Check back in three months.
    One thing we can sure of: dedicated researchers in hospitals, clinic, laboratories ans a computer consoles all over the world are working day and many night to find solutions.
     
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  3. KUMAR5 Registered Senior Member

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    Moreover, we may need to get awnser of these questions :
    1. Whether internalisation of this virus is virus mediated or cellular mediated? Why cells allow this virus to infect them? I think virus is not alive or active before it reach into the cells so it may not be virus mediated.

    2. What can be the maximum virus viable life extracellular and intracellular once it enter the human body?

    3. Does it go into dormancy or latency?

    4. Why it do not cause body to develop sufficiant antibodies and immunological memory?
     
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  5. billvon Valued Senior Member

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    All viruses infect cells.
    Again, we don't know that.
     
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  7. KUMAR5 Registered Senior Member

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    Then nothing is yet clear on developing immunity against it. But we are in urgent need. So, can any antiviral durg or therapy be thought which can logically be effective?
     
  8. billvon Valued Senior Member

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  9. KUMAR5 Registered Senior Member

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    How it can, when it is not alive?
     
  10. billvon Valued Senior Member

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  11. KUMAR5 Registered Senior Member

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  12. KUMAR5 Registered Senior Member

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  13. KUMAR5 Registered Senior Member

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    One more question:

    4. Whether fatal damages to lungs in this infection is virus caused or immune response against it caused?
     
  14. KUMAR5 Registered Senior Member

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    Yes but still, we could not yet find awnsers to basic questions? This virus is quite confusing. How? Probably, God/nature better know?
     
  15. Write4U Valued Senior Member

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    I'm not sure what DMD you refer to but I'm talking about quorum sensing which is achieved by chemical signals which trigger specific responses. By flooding the infected site with chemically altered words, bacteria and perhaps viruses can be rendered non-virulent until they die without dividing or building immunity.

    Bonnie Bassler has an excellent video, which explains "quorum sensing" in plain language.

     
  16. Write4U Valued Senior Member

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    Technically it is not alive because a virus, unlike a bacterium, cannot self-divide. But it can certainly be causal. It uses the host's mitotic mechanisms to divide itself along with the host's cell. If the virus can be made deaf to the cell's mitotic process, that might provide an effective cure.
    Kinda like an in-vivo chemical sterilization.
     
  17. KUMAR5 Registered Senior Member

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    That apply to intracellular state of virus not extracellular state. When it is neither alive or active extracellularily, how can we claim virus mediate infection? It should be cell mediated. Why n how, we need to understand. Moreover internalization is Ace2 receptor based. How cells allow virus to infect?
     
  18. KUMAR5 Registered Senior Member

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    Some drug therapy is there called DMT, DMARDs etc. Depending on diseases, these are disease modyfying types. I need to study your above therapy as new to me.
     
  19. Jeeves Valued Senior Member

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    We do not yet have answers to some specific questions.
    What's confusing about it? It's a virus. It does what all viruses do: it multiplies. Whatever incidental damage it does its hosts is unintentional. When a virus is passed from one host species to another, there is no telling what effect they'll have on each other. If it can't adapt to a new host without killing the host, it will die out. If the virus and its hosts adapt to each other, they both continue. Humans haven't hosted this version before, because it was confined to bats in the wild.
    So we don't know yet how the new arrangement will work out.
    Don't be silly! No God. Just nature.
     
  20. KUMAR5 Registered Senior Member

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    Since virus is not alive extracellularily, no consicious mind, how can we claim infection is virus mediated? Btw, do we have some evolutionary or survival purpose from virus?
     
  21. Write4U Valued Senior Member

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    This may shed some light on the actual mechanism. ( I won't quote, lest it creates consternation..

    Please Register or Log in to view the hidden image!

    ) But viruses use the cell's own mitotic mechanism to procreate. I have a whole thread devoted to this process and the mechanics of electro/chemical information sharing in cells.

    Some illustrations of cell invasion by viruses.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788752/bin/gr1.jpg
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788752/bin/gr2.jpg

    Do check this out; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019765/
     
    Last edited: Apr 30, 2020
  22. Write4U Valued Senior Member

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    But it cannot multiply by itself. It must use a host's mitotic mechanism to multiply, destroying the cell in the process.

    It is actually the perfect parasite, but then 90% of the human biome are bacteria and viruses. Without our symbiotic bacteria and viruses we would die.
     
  23. Write4U Valued Senior Member

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    It's a chemical language. Certain enzymes act as "commands". This is where the term "quorum sensing" originated
    https://en.wikipedia.org/wiki/Enzyme
     

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