Hello, Greetings!! One area is exposed to some new pathogenic Virus. Initially, few people ought to get low grade sub-clinical infection. Being low grade host's immune system is able to treat that and develop immunological memory or natural immunity against it. Then on 2nd bigger infection immune system is able to deal with it. So that infection will be cured. Now suppose we bye-pass this Ist low grade exposure by aggressively avoiding it and directly exposed to 2nd bigger grade infection. WHAT WLL BE THE RESULT?? [ say for example COVID-19 ] Best wishes.