Obviously progress can and has been made but it is not hard to believe that the tools of scientific experimentation can only take one so far. (how is that different from any area of knowledge ,you may ask?) Effectively the experimenter becomes the experiment and perhaps there comes a point when the chances of further success become merely 50/50. And as I claimed earlier the "scientific method" has as one of its raisons d'etre to keep the bias of the experimenter/observer in some kind of check.Does this not become impossible when conciousness and its properties (as in "qualities of pain") have to be included in the equations? Yes ,this "bifurcated reality" does trouble me. I rationalize it as the phenomena of the mind being a subset of the phenomena of the external physical world ,but cannot say why it could not be the other way around. I do see the two "realms" as wildly different even though it is plain that they do affect each other.