Hi Chiller An example of that is AIDS. Terrible disease out of nowhere. It has been said that making predictions are risky, especially about the future. When I make a prediction, metaphorically, I am putting my head on the block. However, I suspect that in 20 years plus, if my predictions are wrong, you won't be able to track me down anyway. He he. However, my optimistic view of the future is based primarily on recent history. Go back a few centuries and look at how life was for humans, and compare it to today. And realise that this improvement is a long term trend. Once, smallpox killed 500,000 people per year. Today it is extinct. Cholera killed hundreds of thousands in Europe. Now rare. Tuberculosis in the 19th century killed one third of the entire population of Europe. It is still around, but kills few in the west. Typhoid was once common and a major killer. Now rare. http://en.wikipedia.org/wiki/Pandemic#Cholera Humans now live long enough for heart disease and cancer to be the major killers. Once, they were considered less important, purely because relatively few people lived long enough for them to be a major problem. I will stand by my assertion that life is better today than any time in history, and continues to improve.