06-20-12, 09:55 PM #101
06-20-12, 10:49 PM #102
So if there is not a known toxic level it can't hurt to keep higher blood levels than the minimum RDA. Those vitamins are relatively cheap so if you have to piss away the excess, so what. If you ever have need for those higher levels you will have added more hours to your total life span. One company that does a great deal of research is the Life Extension Co. Start doing your own research. What's the point of having a computer connected to the Internet if you can't make it work for you?
06-21-12, 12:26 PM #103
Question: Does anyone know much about vitamin K2? I've been seeing more Info about it being a necessary element in heart and artery health. Supposedly, it greatly aids in moving calcium into the bones where it belongs. It's been credited with correcting brittle bones in older people at risk of fractures. It has also been credited with helping to remove calcium build up in the arteries which is a major component of plaque build up in the arteries.
I've seen formulas that include vitamin D3, K2, calcium & magnesium which sounds like a real good supplement combination.
06-21-12, 01:38 PM #104
"Calcium supplements have been widely embraced by doctors and the public, on the grounds that they are a natural and therefore safe way of preventing osteoporotic fractures. [...] It is now becoming clear that taking this micronutrient in one or two daily [doses] is not natural, in that it does not reproduce the same metabolic effects as calcium in food." [...] Calcium supplements might increase the risk of having a heart attack, and should be "taken with caution"...
I can only say that I have not died or been hospitalized yet from an over-coagulation event as the result of taking a mere 100 mcg a day dose of K2, as part of a bone-support formulation that contains no "significant" amount of calcium at all. Of course, there are some products out there that feature much larger doses of K2 (apparently the blended supplements slip under the radar of any USA "limit" for vitamin K). Who knows how reliable those studies are that featured gigantic amounts as treatment with no harmful side-effects. The so-called K2-7 variety, derived from natto, would be the rage over in Japan if you went by the pop-culture press (or at least some years ago when I last paid any attention to this).
06-21-12, 02:16 PM #105
My problem is I am on the blood thinner Warfarin which works by blocking the action of vitamin K. They were not clear about if it blocked only the clotting action alone or all actions. But I do know more vitamin K interferes with the reason I'm taking Warfarin. I'm looking for a happy medium here.
06-21-12, 04:18 PM #106
My problem is I am on the blood thinner Warfarin which works by blocking the action of vitamin K. They were not clear about if it blocked only the clotting action alone or all actions. But I do know more vitamin K interferes with the reason I'm taking Warfarin. I'm looking for a happy medium here. http://www.vitamins-supplements.org/vitamin-K.php
"The only potential problem with high levels of vitamin K supplementation relates to interference with oral anticoagulant medications such as Warfarin and Coumadin, which are antagonists of vitamin K. Patients on oral anticoagulant treatment should not use vitamin K supplements and avoid strong fluctuations in their daily dietary vitamin K intake. However, in a systematic dose-response study of patients on oral anticoagulant therapy, it was demonstrated that the stability of anticoagulation was not significantly affected by vitamin K supplementation at doses below 150 mcg/day. Patients on anticoagulant medications should consult with their physician or healthcare practitioner regarding vitamin K."
Again, however, this would only provide the liver's needs with a little excess (if you were also avoiding vitamin-K rich foods); but still better than nothing as far as trying to direct calcium to the proper places.
06-21-12, 04:54 PM #107
Next I noticed that vitamin E actually enhances the effects of the blood thinner and I'm already taking 800 I.U. per day. My last test was 2.3 up from 2.0 previously.
06-22-12, 10:23 AM #108
But given the conflicting results or increased concern over vitamin E in recent years (links at bottom), even 800 I.U. almost seems a bit risky nowadays (regarding matters other than bleeding), despite that upper limit of 1500 I.U. being set in 2000 before those developments. OTOH, only the dry or water dispersible forms of vitamin E supposedly get absorbed well on a fats and oils empty stomach. That is, most vitamin E supplement users wouldn't be absorbing anything close to the full amount they're taking, anyway, either because of the type or not eating food with their supplements.
On to the aforementioned confusion, the continual flip-flopping that goes on in nutritional research (perhaps reflects the "contingent" factor in science more than any other area of the physical sciences, with the social and psychological sciences probably deserving to be tops in terms of shakiness, uncertainty, and revision):
Use of vitamin E associated with increased risk of prostate cancer
Vitamin E in diet protects against many cancers
No protective effect on cancer from long-term vitamin E or vitamin C supplementation
Vitamin E may increase the life expectancy of restricted groups of men
Putting limits on vitamin E: The potent antioxidant may do more harm than good
High blood levels of vitamin E reduces risk of Alzheimer's
Vitamin E may increase tuberculosis risk in male smokers with high vitamin C intake
Study reveals how one form of natural vitamin E protects brain after stroke
Vitamin E may increase or decrease the risk of pneumonia depending on smoking and exercise
Scientists identify an innate function of vitamin E
Long-term use of vitamin E may decrease COPD risk
Vitamin E may decrease and increase mortality of male smokers with high dietary vitamin C intake
- - - - - -
"One of the most compelling studies of the benefits of vitamin E is the Women's Health Study, in which 40,000 healthy women, 45 and older, took 600 IU vitamin E supplements or a placebo every other day for 10 years. Women taking the supplements had 24 percent fewer deaths from heart disease. Vitamin E's protective effect appeared even stronger in women 65 and older. Those taking the vitamin experienced a 26 percent reduction in cardiovascular events and a 49 percent reduction in cardiovascular deaths."
06-22-12, 11:10 AM #109
That's quite a controversial list of links. I believe some of the most current studies have shown for people over 65 the RDA for vitamin E is way to low and that higher dose shows a significant increase in life span. The test was over 10 years and involved 28,000 over 65's.
As far as my Warfarin levels go. All I can do is keep an eye on my monthly test and if I'm still between 2 and 3, I'm good, if not and I want to stay on my current supplement dosages, I can ask the doctor to adjust Warfarin dosage.
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