06-20-10, 02:39 AM #1
STEM CELL THERAPY and DIABETES CONTROL
My mother's age is 82 years
She has diabetes for last 25 years.
She does not have good control over the disease.
Recently her leg had wound and was not getting cured.
Doctor advised to cut her leg.
Fortunately we tried Stem Cell Terapy.
Within 15 days her leg got cured.
Further her diabetes is also under control.
Stem Cell Therapy involves applying some cream and have some diet control.
Those who are interested can be given details.
06-20-10, 10:52 AM #2
Where can you buy the stem cell cream?
For Type 2 diabetes, one could try Milk Thistle and similar Liver aid such as Neem...
06-20-10, 06:29 PM #3
06-21-10, 03:52 AM #4
See the article below
Stem Cells cure diabetes
"Stem cell transplants 'have freed patients with type 1 diabetes of daily insulin injections'" The Daily Telegraph has said. The news comes after research which allowed volunteers to go, on average, for two and a half years without using the multiple daily injections normally needed to manage their condition.
The small study involved 23 patients with newly-diagnosed type 1 diabetes, a condition in which the immune system can rapidly destroy the insulin-producing cells in the pancreas. These stem cell transplants apparently work by ‘resetting’ the immune system so that the body stops attacking the pancreas. The researchers themselves say that this treatment can only be used when the condition is caught early enough (within six weeks of diagnosis), before the pancreas has been irreversibly damaged and before any complications from very high blood sugar have developed.
The study provides another avenue for research, but this treatment is still at a early stage of development and does come with some side effects and risks. Dr Iain Frame, research director of Diabetes UK, has emphasised that "this is not a cure for type 1 diabetes”.
Where did the story come from?
This research was conducted by Dr Carlos EB Couri and colleagues from the University of Sao Paulo, Brazil along with Dr Richard K Burt from the Division of Immunotherapy, Northwestern University Feinberg School of Medicine in Chicago.
The study was supported by a range of public and private organisations including the Brazilian Ministry of Health, Genzyme Corporation and Johnson & Johnson. The study was published in the peer-reviewed Journal of the American Medical Association.
What kind of scientific study was this?
This was a prospective case series of 23 individuals who had received stem cell treatment to treat new onset cases of type 1 diabetes. This used follow-up data on 15 patients who were first transplanted with stem cells in a study that was previously published in 2007, and combined it with eight additional recruits who joined the study up to April 2008.
The researchers were interested in the effects of the ‘autologous nonmyeloablative hematopoietic stem cell transplantation’ (HSCT), a form of stem cell transplant where stem cells derived from the patient’s own bone marrow are collected from the blood. Around the same time, chemotherapy is used to partly destroy the patient’s own bone marrow cells. This type of stem cell transplantation is a medical procedure most often performed for people with diseases of the blood, bone marrow or blood cancers such as leukaemia.
The researchers recruited 23 patients aged 13 to 31 years (average age 18.4 years) into the study between November 2003 and April 2008. The recruits were mainly men with a short duration of disease (average 37 days) and mostly without previous diabetic ketoacidosis, a dangerous complication of type 1 diabetes.
Participants had a diagnosis of type 1 diabetes confirmed by using tests for high blood sugars and a specific antibody that indicates autoimmune diseases such as diabetes. The average level of this antibody was 24.9 U/mL suggesting the presence of antibodies to the islet cells that produce insulin in the pancreas. Average body mass index at diagnosis was 19.7.
In this study, the researchers released stem cells from the marrow using the drugs, cyclophosphamide and granulocyte colony-stimulating factor. A process known as leukapheresis was used to collect blood and then extract the white blood cells it contained. White blood cells were harvested until progenitor stem cells reached at least 3 million CD34 type cells per kilogram of body weight. To partly suppress the response of the patient’s immune system to stop is attacking the pancreas, they were also given a course of ‘cytotoxic’ conditioning drugs.
The average time from diagnosis to mobilisation of the stem cells from the blood was 37.7 days, and the patients’ stays in hospital for their transplantation lasted around 19 days on average.
The researchers measured C-peptide levels, which are related to the number (mass) of insulin producing cells that remain in the pancreas, with higher levels suggesting that the pancreas is still producing its own insulin. Levels were measured before and during a meal test at different times following transplantation.
The researchers also aimed to record any complications (including death) from transplantation, and any changes in insulin injections required by the participants to maintain their control of blood sugar.
What were the results of the study?
The researchers had follow-up data for between seven and 58 months on each of the 23 patients who received a transplant. They found that 20 patients with no previous ketoacidosis and no use of corticosteroids during the preparative regimen became free of insulin and injections. Twelve patients remained insulin-free for an average of 31 months, and eight patients relapsed and then restarted insulin use at a low dose.
Among the 12 patients who remained free of insulin injections, C-peptide levels had increased significantly at 24 and 36 months after transplantation compared to levels pre-transplantation. C-peptide levels also increased in eight patients who were only temporarily free of insulin injections and this increase was sustained at 48 months after the transplant.
During treatment and follow-up, two patients developed bilateral pneumonia (on both sides of the lungs) and three patients developed problems with endocrine function after more than a year (mostly thyroid problems). Nine patients became “sub-fertile” with extremely low-sperm counts. There were no deaths.
What interpretations did the researchers draw from these results?
The researchers say that at about 30 months following treatment, C-peptide levels increased significantly and the majority of patients achieved insulin independence with ‘good glycemic control’.
The researchers say that at this point in time, their autologous nonmyeloablative HSCT treatment “remains the only treatment capable of reversing type 1 [diabetes mellitus] in humans."
What does the NHS Knowledge Service make of this study?
This was a non-randomised study that did not feature a control group for comparison. As the researchers have stated, randomised trials are necessary to confirm the role of this new treatment in changing the natural history of type 1 diabetes.
There are other points to note:
* Of the 160 patients that volunteered for this trial only 71 were suitable, and of these suitable candidates only 23 opted to participate: the researchers say that although some did not fulfil the strict requirements of the study, such as recent onset of the disease, others declined to participate once they were made aware of the potential adverse effects.
* White male participants were the main recruits so the applicability of this treatment to women and other ethnicities will need further study.
* One of the criticisms of the researcher’s previous study was that the short period of follow-up and the lack of convincing C-peptide data, meaning that there were alternative explanations for the effect seen. For example, the selected patients could have entered a phase of improved diabetic control due to close medical monitoring and physician-directed changes in lifestyle. The researchers claim that this recent study with longer follow-up confirms the treatment effect of HSCT and that the long insulin-free period (over four years one person in this study) is unlikely to have occurred without a true effect of the transplant.
Overall, despite the small number of patients and lack of a control group, this study illustrates a promising approach to treating type 1diabetes in cases where it is caught early enough and patients are willing to accept the adverse effects of treatment. Randomised trials to test the new treatment against current care in a larger group of patients will help establish whether this is truly a ‘cure for diabetes’ or simply a way of prolonging insulin production by a few years.
06-21-10, 08:32 PM #5
Yes, I am well aware of potential stem cell therapies for treating diabetes mellitus. But.....
(i) they are very much trial therapies that are not in routine clinical use
(ii) the delivery of the therapy involves transplantation of cells into the pancreas, not as a cream
(iii) re-establishment of islet cell populations in the pancreas as a result of division of transplanted stem cells and subsequent restoration of normal endogenous insulin levels would not occur in 15 days
(iv) such treatment would not reverse diabetic gangrene in a leg, especially where the leg was close to being amputated.
Your posted material has done nothing to support your original statement.
Last edited by Hercules Rockefeller; 06-21-10 at 08:38 PM.
06-22-10, 04:07 AM #6
I told this example to my friend whose mother is suffering from diabetes for last 5 years.
Her right hand second finger got wound .
The wound was not getting cured.
Kolhapur doctor told there is gangrene and finger needs to cut.
I told my friend to bring his mother to Mumbai.
They visited the clinic at Andheri.
Now she has already started the treatment.
Clinic gave her 10 different medicines and cream for wound
Within two days considerable improvement in the wound is seen.
We also keep a track of sugar level daily.
Let us see the result.
As per clinic within one month she will get cured.
For details see www.space-age.com
Pls note that as per Stem Cell Therapy almost all diseases can be cured.
06-22-10, 04:45 PM #7
06-22-10, 06:35 PM #8
06-23-10, 10:17 AM #9
On a slightly different topic it's known that some drugs contain components synthesised from the metabolism of what ever it was tested on. You'll find this documented both through published medical journals and a few forcively published documents usually found on Animal Rights websites.
Afterall a pill to cure could contain a monkey liver derivative, which isn't so different as taking stem cell research to create a derivative.
06-23-10, 07:49 PM #10
06-24-10, 09:17 AM #11
06-30-10, 12:27 AM #12
Probably the Stem Cell Therapy with Nano Technology help to reactivate our existing cells
thus may have anti aging effect.
06-30-10, 12:37 AM #13
I am glad to inform that my friend's mother's finger is cured though she has diabetes and high suger level.
She is very happy as finger is not to be amputed .
Those who dont believe can visit us.
06-30-10, 02:29 AM #14
For over 30 years stem cells have been used to treat patients with conditions such as leukemia and lymphoma. Stem cells are used in the treatment of a wide range of conditions today with positive and encouraging results.
The following diseases have been treated by various stem cell practitioners with generally positive results:
• Brain Damage
• Cardiac Disease
• Cerebellar Ataxia
• Cerebral Palsy
• Crohn's Disease
• Diabetes Type II
• Eye Diseases
• Heart Disease
• Kidney Disease
• Liver Disease
• Macular Degeneration
• Multiple Sclerosis
• Muscular Dystrophy
• Parkinson's Disease
• Primary Lateral Sclerosis
• Rheumatoid Arthritis
• Spinal Cord Injuries
• Inflammatory Bowel Disease
• Transverse Myelitis
Whether the treatment is appropriate for you, will be determined in consultation with our resident medical practitioner.
Repeat treatments may also be necessary in certain cases – and this will be discussed with you before initiating treatment. We have various plans available that allow you to face the process with confidence, knowing that repeat treatments have been provided for, should they be needed.
Since most diseases treated by us are part of a continuous degenerative process, boosters might be necessary. (booster treatments are usually essential in certain diseases, such as ALS and MS). Stem cells repair and regenerate, and may have limited effect on the progress of the disease itself, although your immune response might be enhanced, slowing down the disease process. The treatment is not a cure – it is a process of repair that occurs at varying levels in different patients and disease states.
After completing the evaluation form, you will be contacted by the Regenecell Patient Counsellor, who will arrange a mutually convenient time for you to consult with the physician.
The Regenecell physician will go through your medical history at length to determine your eligibility for treatment.
Once you are approved for therapy, and payment is received, we will order your cells from our laboratory.
You will also require blood tests which your doctor can arrange or they can be performed at the treatment centre. These will be at your own cost and the results will be available the next day.
Therapy can only progress once these results have been received by Regenecell.
For details see www.regenecell.com
06-30-10, 08:14 AM #15
I call lies. You have just shown that you are really trying to sell quack medicine.
All the stories about your mother are lies.
Obviously, if all this was possible, it would be headlines all over the place.
07-04-10, 04:26 AM #16
Miracles are possible with Stem Cell eeand Nanotechnology.
What is Genetically Modified Cell?
Study on internet about Stem Cell Technology.
vIsit us to see these miracles
Nerul, Navi Mumbai
07-05-10, 05:03 AM #17