A migraine is one of the most common health issues worldwide, affecting up to one in five people. But the mechanisms that drive migraines aren’t well understood. In fact, doctors and scientists are still trying to figure out if a migraine is primarily a vascular or a neurological disorder. A new genome-wide association study published in Nature Genetics suggests that a migraine may primarily stem from problems with the blood supply system. The data in this paper comes from a meta-analysis of 22 genome-wide association studies, a combined dataset of more than 35,000 migraine cases and even more controls. The primary meta-analysis found associations between migraines and 38 independent genomic regions, 34 of which this study associated for the first time with migraines. http://arstechnica.com/science/2016/06/genes-link-migraine-to-blood-flow/
zzzzz............Wake me up when they have something more than a mere association from meta-analysis, i.e. an actual mechanism.
