What is the chemical properties of this drug that make it so powerful?

I would probably have to say heroin. It's a very potent opiate. It is physically addictive. It puts the phsical addiction of nicotine to shame.
Crack might be a close second.

What is the chemical properties of this drug that make it so powerful?

It depends on what you mean by "powerful."

The ONE most common drug that completely and sometimes even permantly alters most of the brain's function is LSD.

By powerful, I mean this can really mess you up. LSD? More powerful than crack or heroin?

It depends on what you mean by "powerful."

The ONE most common drug that completely and sometimes even permantly alters most of the brain's function is LSD.
I agree with you there RO about LSD, it is quite potent, but you can drop a hit or two one weekend and not be violently jonesing for it on Monday like with heroin.
GHB/GBL is extremely potent as well, in the sense that if you take too much of it (which isn't difficult to do), you can pass out and never wake up.

By powerful, I mean this can really mess you up. LSD? More powerful than crack or heroin?

Absolutely! Neither of those other can totally screw up your perceptions (the five senses) to the point that you "smell" sounds and "taste" what you see. And have you ever heard of someone using those other drugs that lept off buildings and out of windows because they thought they could fly? And as I said earlier, in some cases the brain remains cross-wired forever even after never having used LSD again.

But the common perception is that LSD is not as harmful as crack or heroin.

But the common perception is that LSD is not as harmful as crack or heroin.
It is, but in different ways...

Absolutely! Neither of those other can totally screw up your perceptions (the five senses) to the point that you "smell" sounds and "taste" what you see. And have you ever heard of someone using those other drugs that lept off buildings and out of windows because they thought they could fly? And as I said earlier, in some cases the brain remains cross-wired forever even after never having used LSD again
Yes, but while LSD might be more powerful than heroin per se, an overdose of LSD, while can make you go stark raving nuts, it usually won't kill you like an overdose of heroin, or crack can/will. Of all the celebrities who have died on a drug overdose, how many of them were from LSD, Read-only?

Which is worse - death or stark raving nuts?

Which is worse - death or stark raving nuts?
That depends on who you ask. IMO, there are things worse than death. I personally think I'd rather be dead than in some soundproof room in a straight jacket drooling all over myself trying to get away from the talking pink polka dotted elephants.

I'd consider the most "powerful" drug to be LSD as well. Heroin is a "powerful" drug in the sense that it is very strong in keeping you addicted. But that's not what I personally got out of your title. I'd consider powerful, as in potent, or how much it actually affects you.

Yes, there are a lot of heroin addicts that seem to get along fairly well in society using methodone. But, becoming an irreversible fruit cake due to LSD will take you out of the ballgame completely.

I think you need to figure out what criteria you want to use to compare them. Yeah, it's possible that taking LSD a single time could render you permanently wacky, but it's not very likely - you're probably much more likely to end up addicted to heroin after using it a few times than you are to be driven insane from using LSD a few times.

Yes, there are a lot of heroin addicts that seem to get along fairly well in society using methodone. But, becoming an irreversible fruit cake due to LSD will take you out of the ballgame completely.

Yes, but concerning that, you are taking one drug to keep you from being addicted to another drug. How long do you have to keep taking methodone before you are no longer craving heroin? That definintely says something about heroin. It's potency lies within it's physical addictiveness, not in the euphoria itself.

And as far as LSD/hallucinogens and potentcy goes, you guys forgot about PCP; that's a nasty little booger too.

Well, what about PCP?

Well, what about PCP?

http://www.nida.nih.gov/Infofacts/PCP.html

That PCP site is not convincing. It says nothing about PCP turning you into a lunatic permanently.

meth. I've seen it destroy more people faster than heroin. Its cheap, its easy to use, and its easy to get.
Your brain come back from being addicted to heroin, but meth puts holes in your brain that can't be recovered from.

meth. I've seen it destroy more people faster than heroin. Its cheap, its easy to use, and its easy to get.
Your brain come back from being addicted to heroin, but meth puts holes in your brain that can't be recovered from.

I've heard that E can do the same thing to your brain.

LSD is most effective by weight, but I'm going to have to go with DMT, it is way more powerful. A possibile reason is that it is a native brain chemical.

Meth? DMT? E? I'm sorry, but I'm not up to speed (no pun intended) on these drugs. What can they do to mess you up?

Meth? DMT? E? I'm sorry, but I'm not up to speed (no pun intended) on these drugs. What can they do to mess you up?
E-ecstacy (MDMA)-
http://en.wikipedia.org/wiki/MDMA

meth-crystal methamphetamine-
http://www.usdoj.gov/ndic/pubs5/5049/index.htm

DMT-
http://en.wikipedia.org/wiki/Dimethyltryptamine

LSD seems worse than DMT. Ecstacy the worse? Huh? Meth sounds bad.

It is, but in different ways...


Yes, but while LSD might be more powerful than heroin per se, an overdose of LSD, while can make you go stark raving nuts, it usually won't kill you like an overdose of heroin, or crack can/will. Of all the celebrities who have died on a drug overdose, how many of them were from LSD, Read-only?

An overdose isn't the point. You can die from drinking too much water (remember the woman in the drink - don't pee radio contest?).

An overdose isn't the point. You can die from drinking too much water (remember the woman in the drink - don't pee radio contest?).

That's a bad analogy dude. You'd have to drink gallons and gallons of water for H2O poisoning. I'm well aware of it.
And yes, overdosing is the point because it has to do with the potentcy of a drug. Example, let's say there's a nasty little strain of heroin out there that if you took one dose of it at one time, it could kill you. IMO, that makes it more potent than a hit of acid (which would only make you trip for about 8 hours).

And I almost forgot about this one:
http://en.wikipedia.org/wiki/Atropine

Which has similar properties to this (which is classified as a chemical warfare hallucinogen):
http://www.thewednesdayreport.com/twr/bz.htm

Is anyone seriously doing these drugs?

The biggest danger with psychotropics is how seductive they are, from my reasearch I would put crack and crystal meth at the top of the list, perhaps followed by heroin. These 3 drugs are extremely seductive, powerful, short lasting and force the user to crave more and more hits. In the case of crack and meth they are so seductive that people can do them for days on end until they pass out from exhaustion, only to start all over again when they 'wake up' from their stupor, these drugs can kill within a few short years of chronic use completely consuming the subject by the time they die.

Is anyone seriously doing these drugs?


Which ones?
I doubt anyone is doing atropine, as it's not a recreational drug. As for BZ, it's more of a chemical warfare agent, but does its job hallucinogenically. It's like LSD on steriods and crack (no pun intended). If it doesn't kill you, it can make you trip for months followed by some nasty psychosis.
I also doubt that anyone regularly doing crack, heroin, or meth would be a regular poster on here; they probably wouldn't have the coherency or the motivation.

these drugs can kill within a few short years of chronic use completely consuming the subject by the time they die.
Heroin can kill you faster than in a few years.

LSD is most effective by weight, but I'm going to have to go with DMT, it is way more powerful. A possibile reason is that it is a native brain chemical.


Agreed. In terms of potency by weight amount, LSD takes the cake. Only a few micrograms is enough to send someone into orbit.

Diphenhydramine I think messes people up the most because you hallucinate about 900 times more than LSD. And to a sober person you would seem way more out of it.

anyone know anything about kat?

The most powerful is still legal. Salvinorin, derived from Salvia Divinorium. Makes DMT feel like milk and cookies.

The most powerful is still legal. Salvinorin, derived from Salvia Divinorium. Makes DMT feel like milk and cookies.

"Pure" DMT shits all over Salvia, but they're also completely different. Preference, really.

- N

The report of Daniel Seibert first trying salvia is really funny. He thought it was intense but short acting until he realized that he was no longer in his lab, but his long dead grandmother's house, complete with her furniture!

well there are different levels of power. the power of addiction, the power of effect it has on the body, the power of effect it has on the mind. a combination of all of the above. and also you must always take into consideration that all drugs can effect different people in different ways. but a list of very potent and powerful drugs in my opinion are these.

LSD,
crack.
crystal meth.
herion.
MDMA.



peace.

What is the chemical properties of this drug that make it so powerful? Nobody knows. Most street drugs are mixed for the sake of our health. People react differently to different things. 100% pure cocaine is not the same as the coke you buy from "Jose". 100% pure coke will blow your heart and spew your eyes from their sockets. Chemical engineers can even make any drug more potent. By far the most dangerous are hallucigens, I don't know about most powerful.

Meth is the most powerful drug, I've seen what it does to people, its so powerful that it makes those who are addicted but without it a living hell, and life with it a blur of memories.

Yay, perhaps it is so powerful that slaves are being made left and right with this substance. Slaves that like to be slaves mind you... How fucked is that? Happiness in slavery?!?

I'd even go as far to say that meth presents the greatest human weakness of all: the want to be happy and feel good combined with the other extreme want to not feel a groggy hell

The most powerful drug would probably be the one with the lowest LD50 toxicity. It seems that LSD is in the lead here. I've heard that meth is also one of the most dangerous.

I'll agree with sci, and say meth. That shit will age you 20 years in a few months...if "powerful" means screwing your life up the quickest.

http://www.neatorama.com/images/2006-04/faces-of-meth.jpg

I'll agree with sci, and say meth. That shit will age you 20 years in a few months...if "powerful" means screwing your life up the quickest.

http://www.neatorama.com/images/2006-04/faces-of-meth.jpg

That looks like the before and after on one of those make over shows where they end up looking 10 years older instead of younger.:D

According to the bible of drug using comedies " Fear and loathing in Las Vegas", Ether is the most powerful and depraving drug-a real low life commodity. Adrenoquine is also up there. But like I said, many drugs are not 100%. We don't even have 100%alchohol. Abusing 100% alchohol will make you pass out into a coma for 40 days, and you will wake up with temporary amnesia.

I'm surprised meth wasn't mentioned till this page!

I would say meth and DMT are the most powerful....

I'm surprised meth wasn't mentioned till this page!

I would say meth and DMT are the most powerful....

would you now?

I'm surprised meth wasn't mentioned till this page!


It was already mentioned.

How closely related are e and meth, btw?

How closely related are e and meth, btw?

Both MDMA and meth are chemically modified ephadrine I believe. In fact meth amphetamine is so easy to convert from legally available ephadrine products that
even a gcse in chemistry would not be needed. Which is probably why it's use is spreading so rapidly over traditional narcotics.

Both MDMA and meth are chemically modified ephadrine I believe. In fact meth amphetamine is so easy to convert from legally available ephadrine products that
even a gcse in chemistry would not be needed. Which is probably why it's use is spreading so rapidly over traditional narcotics.

The method of manufacture would be simple if basic reagents were available, but the precursors are controlled and watched, and even the precursors to the precursors are strictly controlled.

The process would be normally be way beyond any gcse student.

But to quote two old sayings:
"Where there's a will there's a way"
and
"Monkey See, Monkey do"

If anyone is in any doubt of what harm this chemical can do, do a google on its effects in Thailand.

Both MDMA and meth are chemically modified ephadrine I believe. In fact meth amphetamine is so easy to convert from legally available ephadrine products that
even a gcse in chemistry would not be needed. Which is probably why it's use is spreading so rapidly over traditional narcotics.Ah, GCSE. I haven't heard of that in a while.

The method of manufacture would be simple if basic reagents were available, but the precursors are controlled and watched, and even the precursors to the precursors are strictly controlled.

The process would be normally be way beyond any gcse student.

But to quote two old sayings:
"Where there's a will there's a way"
and
"Monkey See, Monkey do"

If anyone is in any doubt of what harm this chemical can do, do a google on its effects in Thailand.

Seriously, if you can bake a cake you can purify ephadrine based cold medicine into crystal meth.

PS If it makes any difference I have a grade A gcse chemistry .

What school did you go to, St Trinians? :)

btw I've looked up Thailand myself and the situation is a bit better now than it was in 2003. The police were then operating a shoot on sight policy.

I think you have to take a statistical view of this. The worst known effect of a drug is arguably not as important as its median effect.

If you ask me personally, it's caffeine. I lived through the 1960s and 1970s, I've tried drugs that I won't list on a medium monitored by government agents, protected only by a pseudonym they could hack in 8.5 seconds. None of them--none of them--caused me as much grief as caffeine.Caffeine changes not just my mood but my whole personality. It makes me angry, rude, loud and irritable. It makes it almost impossible to sleep that night. So I get up the next day not only in caffeine withdrawal, but also dead tired, needing another hit. After three days of this I'm useless, dangerous and friendless. On a caffeine bender--some of which have lasted for years--I have lost friends, wives, jobs, educational opportunities, weight, and quite a few other things that I won't list.No other drug--not even ones I became addicted to--screwed up my brain and my life as badly as caffeine. I am still and will always be a recovering caffeine addict, and I'm not even very diligent about staying on the wagon.

So there's your analog to the jumping-off-the-roof or staring-into-the-sun-and-going-blind LSD anecdote. All drugs affect each of us differently. Most people don't react as I do to caffeine and most people don't do crazy stuff when they lick acid.

What's the average experience, or the median? By that measure LSD seems to be as benign as marijuana. Particularly since in a significant number of people it has the same effect as marijuana of opening up new cognitive pathways and sparking increased creativity that is not lost when the drug wears off. Or as I suspect, suppressing the logical processes that have come to dominate our lives so that the other half of our brain can have a chance to be in charge.

And don't forget the perturbation of illegality on the effect. When heroin and cocaine were legal, people of my grandparents' generation knew doctors and lawyers who were addicted to it but it didn't interfere with their work or the rest of their lives any more than caffeine addiction does to today's doctors and lawyers.

If you want to talk about the most likely effect of a drug on the average user (not someone who is already looney and just needs a push over the edge, i.e. the people most likely to want to try drugs), in my observation that would make crack and meth the worst. I admit that I don't know people who use these new alphabet-soup drugs so I can't comment on them. But the last thing I would trust is "official" reports that highlight the worst cases.

hmmm ok

crack really isnt that strong... in my experience weed beats it
LSD is stronger, and can blow someone away
salvia can be very strong but the trip's duration is something like 10 minutes. which is absolutely petty compared to a
5 hour DMT trip (I refer to ayahuasca) which to me has been the most intense.

but to say which drug is more powerful entails ambiguity resolution and some categori - actually it is completely dependent on your dosage

10 tabs of LSD might equal a cup of Ayahuasca (which is also completely variable ie. how much microdots in a tab, and how much bark boiled in the pot.

hmm so as I try harder to say which is more powerful it becomes obvious it is an impossible question

just remember most of what you know, outside of experience is highly saturated with propaganda

Seriously ignore me .:)

Nah seriously you are fucking spastics .

No other drug--not even ones I became addicted to--screwed up my brain and my life as badly as caffeine. I am still and will always be a recovering caffeine addict, and I'm not even very diligent about staying on the wagon.

That is some outrageous claim. Guess every one is different.

What is the most powerful illegal drug?

To answer you need to be specific: Stimulant or Depressant.

They can be equally powerful as far as the ability to kill. At opposite ends of spectrum would be heroin and Cocaine, but there are substitutes.

Plus it depoends on what music your listeneing to.

We have got to get it together
We have got to get it together now

Lock up the streets and houses
Because there's something in the air

wank

That is some outrageous claim. Guess every one is different.And that is exactly my point. It is outrageous. So are the claims of people dropping acid and diving into empty swimming pools. And my claim is just as real as theirs. (Well some of those are urban myths but there is a kernel of true stories beneath the mythology.) And I am just as much a one-percenter as they are. There are others. I'm trying to Google the Civil War general one of my caffeine detox therapists told me about who rode into battle swinging his sword like a berserk Visigoth instead of staying on the hill with the other high ranking officers. Turns out he was wigged out on coffee, which apparently had become widespread just in time to make the Civil War even crazier than it already was.

Everyone is different. But most people are not one-percenters. That's why they call us that.

Which ones?
I doubt anyone is doing atropine, as it's not a recreational drug. As for BZ, it's more of a chemical warfare agent, but does its job hallucinogenically. It's like LSD on steriods and crack (no pun intended). If it doesn't kill you, it can make you trip for months followed by some nasty psychosis.
I also doubt that anyone regularly doing crack, heroin, or meth would be a regular poster on here; they probably wouldn't have the coherency or the motivation.

.......................

Youd be surprised how many highly functional, intelligent and talented people get mixed up with drugs, espescially heroin.. personally ive never touched the stuff id probably like it too much.. lol



[QUOTE=Chatha;1478812]Nobody knows. Most street drugs are mixed for the sake of our health. People react differently to different things. 100% pure cocaine is not the same as the coke you buy from "Jose". 100% pure coke will blow your heart and spew your eyes from their sockets. Chemical engineers can even make any drug more potent. By far the most dangerous are hallucigens, I don't know about most powerful.

i did some about 90% a couple weeks ago and it was amazing.. i went to sleep after about 15 min after doing it.. along with everyone else that did it.. and yes it was definitley coke.. lol

According to the bible of drug using comedies " Fear and loathing in Las Vegas", Ether is the most powerful and depraving drug-a real low life commodity. Adrenoquine is also up there. But like I said, many drugs are not 100%. We don't even have 100%alchohol. Abusing 100% alchohol will make you pass out into a coma for 40 days, and you will wake up with temporary amnesia.

HAH LOVE this movie !! "you took too much man too much" :DDD

hmmm ok

crack really isnt that strong... in my experience weed beats it


crack is stronger than weed. i have never personaly tried crack, but i did used to cook it up and sell it. i used to smoke weed and sell that aswell, and one thing i know is that weed cats are not as fucked up as crack heads. all you have to do is look at the state of your average crack addict, and compare him to your regular weed smoker.


in terms of what is more powerful in addiction andhow much it messes you up, i would say crack is alot worse than weed.



peace.

I also doubt that anyone regularly doing crack, heroin, or meth would be a regular poster on here; they probably wouldn't have the coherency or the motivation.

dont forget they would have already sold the computer required to post long ago, to buy more crack, heroin or meth.


peace.

not all drug addicts are poor :) just look at some musicians.. then again theyre probably too busy partying and nailing groupies to tap away at a keyboard..

In terms of effects I'd say DMT, potency would be LSD and "fucks up your life" would be meth.

DMT is one of the few substances that can cause true hallucinations, not just visual distortions of what's already there.

But that's just in general, different drugs affect people in different ways.

crack is stronger than weed. i have never personaly tried crack, but i did used to cook it up and sell it. i used to smoke weed and sell that aswell, and one thing i know is that weed cats are not as fucked up as crack heads. all you have to do is look at the state of your average crack addict, and compare him to your regular weed smoker.


in terms of what is more powerful in addiction andhow much it messes you up, i would say crack is alot worse than weed.



peace.

I don't know, crack seems like a strong cup of coffee compared to weed.

I don't know, crack seems like a strong cup of coffee compared to weed.

id tend to agree as far as effect of the drug.. crack never did a thing for me, though the addiction would seem to be a lot stronger with it. maybe i just never got the "good crack"

LOL

In terms of effects I'd say DMT, potency would be LSD and "fucks up your life" would be meth.

DMT is one of the few substances that can cause true hallucinations, not just visual distortions of what's already there.

But that's just in general, different drugs affect people in different ways.


i like this answer.. but.. what the hell are "true hallucinations"?? :D

My best friend was a crack addict, i knew him long before he became addicted. I never smoked crack myself.

I saw him smoke one time, his back hunched up like a warewolf, then he would prance around on his tippy toes with an evil look on his face. he knocked stuff off his desk, hid stuff behind furniture. the one time i seen this behavior i grabbed a steak knife and held it behind my back, waiting for a move towards me, for i knew that i was witnessing somehting beyond his ability to control, beyond this persons rational limits. i would have had to...curse the thought, this was the personification of depravity, hiding in a dark room, unable to function, unable to speak. grunting, sweating, crawling across the floor.

He is dead now from smoking crack. This was the tail end, i think his brain was truly damaged by that point.:shrug:

yeah.. thats wild.. it most definitley must alter brain chemistry more and more over time, i have a similarly very sad story as well... and i am very sorry to hear of your loss.

crack is stronger than weed. i have never personaly tried crack, but i did used to cook it up and sell it. i used to smoke weed and sell that aswell, and one thing i know is that weed cats are not as fucked up as crack heads. all you have to do is look at the state of your average crack addict, and compare him to your regular weed smoker.


in terms of what is more powerful in addiction andhow much it messes you up, i would say crack is alot worse than weed.



peace.

nah comparing the two won't tell you which experience (smoking crack, or smoking herb) is stronger. too many other variables.

in my experience crack was weaker

nde is the most powerful drug.

life/death is the most powerful drug. everything is a drug.

there are no drugs because drugs are a type of food. the difference between heroin and a strawberry is that heroin tastes better.

nde is the most powerful drug.

life/death is the most powerful drug. everything is a drug.

there are no drugs because drugs are a type of food. the difference between heroin and a strawberry is that heroin tastes better.

Heroin tastes better than Strawberries???

So why have we never heard of "Heroin and Cream"?

And Why do Cops in Copshows taste a dab of Heroin on their finger and say "Yes, that's Heroin"
Surely they should go "Mmmmmmh, now that's some tasty Heroin. Where's the Creamjug?"

This is a slight deviation from the direction this thread has taken so far, but here is my question:

Which illegal drug is considered as having the most powerful "high"?

Heroin tastes better than Strawberries???

So why have we never heard of "Heroin and Cream"?

if it doesn't taste good, why do people eat it?

Which illegal drug is considered as having the most powerful "high"?"High" is an oversimplification. Drugs take people in many directions, not just one that could metaphorically be described as "upward" as the word implies. There are intoxicants (alcohol), hallucinogens (psilocibin), psychedelics (LSD), soporifics (opium), stimulants (amphetamine), mood levelers (nicotine), and many others, and those are just their most common primary effects. Some people want a drug that makes them alert, some want one that suppresses their logic and allows them to focus on their creativity, others want one that just makes them feel like it's okay to be irresponsible. It's hard to compare the strength of these various effects. A person who appreciates going in one direction might not be willing to take enough of a drug that goes a different way to be able to evaluate it. And even then what's he going to say? "I got really peaceful on the marijuana but the silliness I felt on the alcohol was more powerful."

Yes, but while LSD might be more powerful than heroin per se, an overdose of LSD, while can make you go stark raving nuts, it usually won't kill you like an overdose of heroin, or crack can/will. Of all the celebrities who have died on a drug overdose, how many of them were from LSD, Read-only?

It's nice to see someone who isn't brainwashed by retarded propaganda. So good that you researched this, too.

Xelios:

DMT is one of the few substances that can cause true hallucinations, not just visual distortions of what's already there.

Never did enough, I guess. But what about ketamine or dxm? Both are classified as dissociatives, but they come closest to fulfilling your criteria for "true hallucinations."

As for the strongest drug: for dependance, I'd say caffiene. Coming down off meth (I have heard *cough cough*) is easier than going without any caffiene for a day. For potency per volume, I'd say LSD and for strength of effects, I'd say peyote or special k.

domesticated om:
Which illegal drug is considered as having the most powerful "high"?

I echo fraggle rocker's sentiments - but in terms of rush and sheer awesome "up," probably coke.

Combining stuff is a whole different trip of course.

Kittyflipping FTW!!

Haven't done anything in ages but my mix was weed and coke. And poppers if I was taking a walk on the wild side. Reason being that the coke tempered that god-awful thinking in my head, and got me off my ass. Also, the paranoia was contained and I could zig-zag down a street at night without running into anyone. I always hated tripping on a coach. But not in bed. Lol.

I am happy to have found this thread as i was exactly looking for the same question.

Fortunately the question itself is already unsharp, so all the answers really helped me.


So after reading these answers, i found out why i was asking for the most powerful drug. This can be split into several levels of importance:

- addictiveness (which is for me absolutely not interesting, ofcos)
- alteration of physio-mental-condition (like doping)
- alteration of psycho-mental-condition (hallucinogenic)
- controllability

From that view, i would say the most powerful drugs are like mentioned before on opiate-basis. But i also agree with the intensity of caffeine addiction and even nicotine.

As far as i can speak for myself i have tried some stuff, but stayed away from underground-laboratory-alchemy. So i did never take LSD, Heroin or the like, but i experimented a lot with natural drugs and also meds.

I frequently consumed a combination of THC and Amanita which really gave me strong demons and even near death experiences. In some cases i even added meds like tranquilizers (non-benzo) and the like. Since this is a mixture and not a basic drug, it does not count as a powerful stand-alone, but i am able to measure my experiences and compare them to reports of others.

I believe i have always, including my alcohol&meds experiments, landed somewhere between LSD and Heroin. Somewhere along the way, mostly aside the road, puking and begging god for mercy :-D

The most extreme and intense thing i have *ever* experienced and which is from what i read and heard of it, one of the most powerful things to *really* fuck your mind up, the demon itself: DXM.

I am happy it was only an accident and i am happy i survived it and i am happy i must never take it again. I did not know that if you take DXM and are a Nicotine addict (smoker), you can experience something like a "fever explosion", which felt like an atom bomb was dropped inside my mind. I had to see the doctor after the experience and i had a 5 or so hours ultra horror trip, being really so ultra far away that i begged to god, please don´t let me die (and i am an agnostic).

I have read and heard that others had even worse experiences which included unavoidable, unescapable hallicunations, being shut off like comatose, dead alive and stuff like that.

I have also heard that some take it regularily, to reach these "plateaus" (danger, danger, folks) or even combine dxm with other substances (ultra danger, folks!!).

I thought the effects i had were an accident, and the stuff i saw was due to overdose and poisoning. But when i got informed, i read, these effects are desired. Go look for yourselves -> erowid.

As i write this, i still feel upset about that stuff. Thats now 12 years ago. I consider that powerful.

best regards,
kollege

Absolutely! Neither of those other can totally screw up your perceptions (the five senses) to the point that you "smell" sounds and "taste" what you see. And have you ever heard of someone using those other drugs that lept off buildings and out of windows because they thought they could fly? And as I said earlier, in some cases the brain remains cross-wired forever even after never having used LSD again.

Courtesy of Bill Hicks:

Did you ever see a positive drugs story on the news?
Never. News is supposed to be objective. Isn't it supposed to be THE NEWS? But every drugs story is negative.
Well, hold it: I've had some killer fuckin' times on drugs. Let's hear the whole story.
Same LSD story every time, and we've all heard it: 'Young man on acid. Thought he could fly. Jumped out of a building. What a tragedy.'
What a dick! He thought he could fly? Why didn't he take off from the ground, and check it out first?
You don't see ducks lined up to catch elevators to fly south.
How about a positive drug story for once?
Wouldn't that be newsworthy? Just once?
To base your decision on information rather than scare-tactics and superstition and lies?
Just once? I think it would be newsworthy."

"Today a young man on acid realized that all matter is merely energy condensed to a slow vibration, that we are all one consciousness experiencing itself subjectively, there is no such thing as death, life is only a dream, and we are the imagination of ourselves.... Here's Tom with the weather."

I would say that GREED and POWER are the two most powerful illegal drugs that humankind has ever known.

LSD is most potent dosage wise (0.1g is max effective dose but that's tim leary strength).

If you mean potential for ruining lives then thats any psychotropic substance thats available. Even weed can do it (especially high THC low CBD stuff). If you have a genetic predisposition it's even more dangerous. I have a close friend who ended up mentally ill for 5 years including hospitalisation (mental health hospital I mean) from cannabis psychosis. If you abuse anything it will burn you, unfortunately I have seen this too many times.

Individual use does change so impact on life from a drug varies too, using heroin once a year is not as damaging as using speed once a day for instance. However some might seem more addictive but even still personality and individual metabolism and genetics etc plays a part. Some things do seem very damaging, which can be accredited to the impurities as well as the drug itself. Meth, crack and heroin spring to mind.

Meth cooked up from suzy reduction method is dirty. Often polluted with unspent reactants including MEK (methyl ethyl ketone, if you are unfamiliar basically NOT NICE STUFF), toluene, HCl etc etc. When cooks suppliment chemical reagents that are easy to trace with stuff like the contents of batteries it gets even dirtier.

Heroin is the same. Average street purity is around 4% (hence people do quart gram bags in one and don't turn blue, 250mg will kill most people). When it's made from homebake methods it's even dirtier, such as the codeine demethylation method which leaves all kinds of crap in the stuff like NaOH, HCl, pyridine compounds etc. It's not even heroin although is sold as that. It's morphine (or slightly modified depending on raw material) no diacetylmorphine (heroin, which has even nastier reagents again).

Take into account the chemists who make it do so cheaply and without purifying so impurities remain such as unspent reagents. Also yields dictate you wont get 100% conversion as most will know 100% yield reactions are rare. There will remain plenty of unspent reagent and intermediates and byproducts in the final (pure) product.

Then people with no knowledge of chemistry or pharmacy cut the stuff with bulking agents and secondary effect drugs (usually cheap to give slightly different effect like ketamin, caffeine, ephedrine and like in speed and E, diphenhydramine and like in cheese heroin). These people don't understand yields and think the stuff is 100% pure when comes out the labs. The further down the line it goes the dirtier it gets.

opium?

Did you know there's a synthetic ester of THC that's 200 times stronger than ordinary THC?
It's a stereoisomer, and can't occur naturally. Being that strong, it's in the same league as LSD - you need micrograms, not milligrams.

P.S. The US Army spent gazillions growing and synthesizing THC and its analogues, back in the 70s. They apparently developed some pretty mean cultivars.

LSD is most potent dosage wise (0.1g is max effective dose but that's tim leary strength).

If you mean potential for ruining lives then thats any psychotropic substance thats available. Even weed can do it (especially high THC low CBD stuff). If you have a genetic predisposition it's even more dangerous. I have a close friend who ended up mentally ill for 5 years including hospitalisation (mental health hospital I mean) from cannabis psychosis. If you abuse anything it will burn you, unfortunately I have seen this too many times.

Individual use does change so impact on life from a drug varies too, using heroin once a year is not as damaging as using speed once a day for instance. However some might seem more addictive but even still personality and individual metabolism and genetics etc plays a part. Some things do seem very damaging, which can be accredited to the impurities as well as the drug itself. Meth, crack and heroin spring to mind.

Meth cooked up from suzy reduction method is dirty. Often polluted with unspent reactants including MEK (methyl ethyl ketone, if you are unfamiliar basically NOT NICE STUFF), toluene, HCl etc etc. When cooks suppliment chemical reagents that are easy to trace with stuff like the contents of batteries it gets even dirtier.

Heroin is the same. Average street purity is around 4% (hence people do quart gram bags in one and don't turn blue, 250mg will kill most people). When it's made from homebake methods it's even dirtier, such as the codeine demethylation method which leaves all kinds of crap in the stuff like NaOH, HCl, pyridine compounds etc. It's not even heroin although is sold as that. It's morphine (or slightly modified depending on raw material) no diacetylmorphine (heroin, which has even nastier reagents again).

Take into account the chemists who make it do so cheaply and without purifying so impurities remain such as unspent reagents. Also yields dictate you wont get 100% conversion as most will know 100% yield reactions are rare. There will remain plenty of unspent reagent and intermediates and byproducts in the final (pure) product.

Then people with no knowledge of chemistry or pharmacy cut the stuff with bulking agents and secondary effect drugs (usually cheap to give slightly different effect like ketamin, caffeine, ephedrine and like in speed and E, diphenhydramine and like in cheese heroin). These people don't understand yields and think the stuff is 100% pure when comes out the labs. The further down the line it goes the dirtier it gets.

:bravo: Good post Creept'!

As for crack strong crack will drop you. I mean completely drop you. Most is made from Cocaine HCl with the HCl salt being converter with sodium bicarb. Since it's often end users who do this the coke HCl is often shit. Take into account my post above. Then the reaction leaves a load of salt (NaCl, table salt) in the mix. Drying it out makes a cracking noise as crystal forms and water leaves hence the name. Much of the coke these days is benzocaine, lignocaine. lidocaine, ephedrine, pseudoephedrine (suzy), caffeine, glucose, fructose etc laced with some people even using non active bulking agents like milk powder.

If you made pure Cocaine base crystal with good pure HCl and good reagents and purified it checking it's melting point to get as close as possible it will do more than be a strong cup of coffee.

Did you know there's a synthetic ester of THC that's 200 times stronger than ordinary THC?
It's a stereoisomer, and can't occur naturally. Being that strong, it's in the same league as LSD - you need micrograms, not milligrams.

P.S. The US Army spent gazillions growing and synthesizing THC and its analogues, back in the 70s. They apparently developed some pretty mean cultivars.

F* me I didn't know that, lets hope that doesn't become available on the street. THC alone is a pretty nasty trip.

For the betterment of science you should make this up for us and we'll test it out for you.

Give me a place to cook and I will. Only joking I don't even do drugs now. Although I have in the past I am clean these days. THC can be purified easily but although I never tried it everyone I know who has say it puts you on a downer pretty quick. Just makes you depressed and heavy. Medical stuff it is the same but they started mixin with CBD like occurs in natural unmoded plant to stop ill effect (bad effect, not speaking in ebonics meaning good effects). I watched a program about this not too long back but remember howard marks used to do something similar.

Give me a place to cook and I will.

TOO LATE. You already said you will. Can I call you Mickey Rourke from now on?

TOO LATE. You already said you will. Can I call you Mickey Rourke from now on?

"Johnny fave whit".

That was a good post indeed Creepto. I still say most cocaine sold today is just cut with meth\speed. And you are right that stuff is often like battery acid, i can only imagine whatg it does to the vascular sytem.

Nothing good comes from hard drug use. I am pretty sure a tiny line of heroin will send you for a loop compared to a hit of crack. The thing is that first time use and long term use is a big difference when it comes to how 'powerful' a drug really is.

"Johnny fave whit".

Exqueeze me?

Exqueeze me?

Mickey Rourke circa ..Oh fuck, what was it?
Angel Heart, that's it ( Lisa Bonet looking hot, Mickey passing for someone who could act, De Niro in a forgettable role), anyway..Mickey Rourke.

BTW, how badly miscast was he in 9 and a half weeks?
And kimmie was shithouse too.

I like him in Sincity, funny since he looks a bit like Marv without makeup like Ron Perlman looks like hellboy and other mutants.

The one that scares me the most is probably LSD, though any substance that fucks with your mind and makes you not yourself is fucking sketchy, and I don't see how anyone could do that for pleasure.

Adrenoquine is also up there. But like I said, many drugs are not 100%.

Did you mean to type Adrenochrome? I just ran a search on the word 'adrenoquine' and found nothing except your post in the search results.

I didn't know adrenochrome was that powerful, I thought it was like a lesser version of LSD.

Strychnine

for potency ...LSD wins hands down....for addictivness...either meth or heroin.

What is the chemical properties of this drug that make it so powerful?

I simply can't be arsed reading the posts, but if anyone has said this i apologise, but i would reckon tobbacco is the most addictive drug.

I simply can't be arsed reading the posts, but if anyone has said this i apologise, but i would reckon tobbacco is the most addictive drug.

Good one. You may be right.

:) thank you enny!!!

I simply can't be arsed reading the posts, but if anyone has said this i apologise, but i would reckon tobbacco is the most addictive drug.

Yes. Most likely it is. As a matter of fact one person addicted to crack i spoke to told me that same thing. He sais it is harder to quit smoking cigs. than crack but tbh he never coud quit the crack either because he died while on a binge. soooooooooo....

it's certainly one of the most widespread damaging ones but it's not illegal (it should be). It's a nasty nasty drug, there is a footpath not far from where I live where industry used to dump nicotine waste (people call it the nicotine footpath). Nothing grows there, just slabs of nicotine. My biology lecturer told me about it first.

Mickey Rourke circa ..Oh fuck, what was it?
Angel Heart, that's it ( Lisa Bonet looking hot, Mickey passing for someone who could act, De Niro in a forgettable role), anyway..Mickey Rourke.

BTW, how badly miscast was he in 9 and a half weeks?
And kimmie was shithouse too.

Sorry but I saw him in Wild Orchid when I was young. Before the days I was taught how to spoof hardcore stuff. You know Red Shoes Diaries kinda stuff. And he was HAWT. And as Marv he was a bit of a physical mess but I dare any woman to pass up that testosterone engorged example of masculinity. Nothing like a man for a man's job I reckon.

for potency ...LSD wins hands down....for addictivness...either meth or heroin.i would reckon tobbacco is the most addictive drug.
Addictive drugs are actually just half of the equation, the other half is what a human body (or a mammalian one, like a mouse or a rat), does when metabolising them, and long-term changes in physiology, neurotransmitter regulation, and a whole bunch of stuff.

P.S. Methadone is more addictive than heroin, or at least withdrawal symptoms are more severe and longer-lasting, but heroin is preferred because the rush and ensuing narcosis is "better", even though 'done lasts at least twice as long.
The addiction to methadone issue is apparent with modern-day prescription, or "maintenance" of dependency for opiate addicts.

I registered here to reply to this post since no one has mentioned the opiates stronger than heroin.

Fentanyl is a synthetic opioid that can be up to 100x more potent than heroin and the ld50 is 0.5mg-1mg. I first ran into fentanyl back in my morphine days. Nobody had any morphine, but a guy said he could get fentanyl patches which were, he said, a substitute for morphine. That was all I needed to hear. I had done morphine every day, sometimes in amounts exceeding 250-350mg, for over a year. I still managed to work and paint, but it got to the point that I couldn't be happy without having morphine. So after being out for little over a day, the desperation began to set in. Anyone who has been addicted to an opiate knows that kind of craving. Unable to find my drug of choice, I bought 10 25mg fentanyl patches. It was a gift in disguise. I don't remember how many I used, but I remember pulling over at a gas station and wobbling into the bathroom. My skin was cold and clammy and I just laid against the bathroom wall, unable to move. I was higher than I had ever been in my life. The tiles and stalls and toilets started to take on a glowing quality. They almost looked holy. Anything strong enough to make a convenience store restroom look majestic is pretty powerful. I don't remember anything between passing out and waking up in the hospital. I have been clean (from opiates) ever since.
I always preferred morphine to heroin, and maybe I'm alone in that, but I had done heroin more than a couple of times. Compared to fentanyl, heroin is tylenol.
Stronger still is an analogue of fentanyl, Carfentanil.
Carfentanil is roughly 10,000x more potent than morphine, 4,000x more potent than heroin, and 100x more potent than fentanyl. In terms of raw power, Carfentanil is probably the most powerful drug. It's lowest median effective dose is 0.00032 mg.

So unless you're a wild animal weighing in at over 1,000lbs, I'd stay away from it.

The strongest hallucinogen I've ever experienced is brugsmansia. At the time of my first experience with brugsmansia I had done LSD, LSA, mescaline (my favorite), ayahuascha, all manners of mushrooms, DXM, ketamine, salvia, datura, etc ... more than I should have in truth. I've had scary experiences with these drugs, and sublime experiences as well. DXM and salvia can be terrifying, especially with someone prone to anxiety and panic attacks (such as myself) but the pure terror of brugsmansia surpasses them all. At least for me, anyway. I was not even seeing the same world my friends were seeing. With LSD there are perceptual distortions (breathing walls, glowing colors, etc) but with brugsmansia all of my senses were feeding my brain incorrect information. In reality, I was spazzing out on a couch. In that other world, I was playing hide and seek with some sort of creature. It never gave me enough time to hide so I was always running. Anxiety nightmare. Possible seizure. Terrible. LSD is pretty tame by comparison. Again, this is personal experience and might differ greatly from person to person.

Hope this helps.

wow