Hi all,

I want to know which medicines are commonly prescribed for:-

1. Increasing stomach acid.

2. Increasing & lowering the bile/its secretions.

3. Increasing & lowering the pacreatic bicarbonate/its secretions.

About Antacids: I want to understand, how differant antacids can be prescribed differantly in differant conditions. I mean, if all antacids are prescribed,similarly-- as antacids or differantly?

Thanks.

I just studied. Some important and can mean 'just opposite' aspects about antacids seems to be not given importance & usually ignored.

Acidity with Constipation or uncler motions and Diahrrea/ or clear motions can/should be two basic conditions of prime importance in deciding antacid type. We should understand these two basic conditions which are effected or may effect 'so many things, inside. However, it looks that this consideration is usually less attended or taken bit carelessly. Its opposite may mean just opposite. Look at Magnessium & Aluminum based antacids.

"Antacids & acid blocker may be differanciated by their Antacidic+ Laxative- hyperosmotic-saline , Antihyperphosphatemic, Antihypocalcemic & Antiurolithic (calcium calculi) effects along with their effects on GI & internal pH, infections, inflamations, digestion & absorptions of body subtances etc.."
http://www.drugs.com/xq/cfm/pageID_0/htm_202047/type_cons/bn_Antacids/micr_medex/qx/index.htm
http://www.bbc.co.uk/health/ask_doctor/antacid_medicine.shtml

What are the 'Cordinated processes' related to digestive pH in body?

I am only posting. This can be most basic but most important & constitutional or systematic type understanding.

Is is the right way to make & prescribe any antacid mixed with the salts of opposite/differant types ( unclear/clear motions etc.) of effects? :confused:
http://www.drugs.com/xq/cfm/pageID_0/htm_202047/type_cons/bn_Antacids/micr_medex/qx/index.htm

" imbalances in digestive pH/secretions can cause imbalances in digestions and so imbalances in absorptions of all or most body substances resulting the imbalances in various body substances & imbalances in internal cordinated activities/environment relating to all or most of these body substances along with the problems & complications related to imbalances in all or most body substances-- a constitutional/systematic/miasmic type effect."

How much it can be true?

I can't offer you any insights here Kumar. I don't know much about the GI system.

Really so? Anyway thanks, we can think it. Pls contribute in other topic "Diabetes: If Mitochondrial disease?" in this forum.

Hei Kumar,

I heard that the glial cells regulate the pH of the fluid between neurons.

Thought you might find that interesting since you seem to be fond of the topic of pH.

Thanks for the indication. I shall study it.

Regulation and Modulation of pH in the Nervous System
Physiological signalling mediated by changes in cytoplasmic pH has been documented in a wide variety of cell types. Often, growth factor or classical hormone receptors are coupled to the activation of H+ transport, resulting in pH shifts over minutes to hours. In the nervous system, however, electrical signalling takes place in milliseconds to seconds. Recently, mechanisms have been discovered which can modulate pH on an equally rapid time scale.
http://www.med.nyu.edu/Research/M.Chesler-res.html

Can any substance(pH related) is absorbed across mucous membrane/under the tongue in mouth--can trigger above activity in normal cells & in nervous system?

Carbonic Anhydrases
Breathing is a fundamental function in life - ever wondered what really happens when we breathe? The air we breathe in has precious oxygen that fuels the breakdown of sugars and fat in our cells. In our lungs, oxygen diffuses into the blood, binds to hemoglobin and is transported to all the cells of our body (see the Molecule of the Month feature on hemoglobin). Carbon dioxide is a byproduct of sugar and fat breakdown in cells and needs to be removed from our body. Again, blood acts as a transport medium....
..Carbonic anhydrase is an enzyme that assists rapid inter-conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. This enzyme was first identified in 1933, in red blood cells of cows. Since then, it has been found to be abundant in all mammalian tissues, plants, algae and bacteria. This ancient enzyme has three distinct classes (called alpha, beta and gamma carbonic anhydrase). Members of these different classes share very little sequence or structural similarity, yet they all perform the same function and require a zinc ion at the active site. Carbonic anhydrase from mammals belong to the alpha class, the plant enzymes belong to the beta class, while the enzyme from methane-producing bacteria that grow in hot springs forms the gamma class. Thus it is apparent that these enzyme classes have evolved independently to create a similar enzyme active site.http://www.rcsb.org/pdb/molecules/pdb49_1.html

It looks to be very interesting to understand.