How to foil a genetic fingerprint

Discussion in 'Biology & Genetics' started by Trilby, Nov 20, 2008.

  1. Trilby Registered Member

    Messages:
    1
    Suppose for a moment that I am planning a major heist.

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    Naturally I would not want the authorities to be able to generate a DNA profile from traces I left behind.
    They might later catch me and use that to indict me, after all. They can be very mean sometimes.

    So, what sort of chemicals could I scatter around the crime scene to foil DNA analysis? Which contaminants will inevitably spoil any PCR rection?

    Antibodies tuned to polymerase might work, but would be far to expensive.

    Would calcium hypochlorite powder work? Or powdered lead?
    Any easily available chemicals?

    (the easiest solution would probably be to scatter around cigarette buts from public ash trays. That way they would not know which DNA traces are from innocents, but that sounds boring)




    Second question:
    Suppose this heist goes wrong, as they tend to do. The authorities are able to get a genetic fingerprint, and I as a suspect have to give up a DNA sample for comparison.

    But luckily I have some cash left from my heist. What could I do to foil this DNA sample?

    If I get the DNA of some other person (cigeratte but), could I perform a PCR myself, then inject the resulting amplicon into my blood just before they take the sample?
    Or wash my mouth with it, if they take cells from there?
    Would that throw of their analysis, since my own dna is drowned out by the preamplified short strands?

    How hard is it to get the same primers that the police uses? could I somehow work without these specific primers?
    How hard is it to get the polymerase?


    Looking forward to your answers

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